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LYPD3 抗体 (AA 90-392) (HRP)

The 兔 多克隆 anti-LYPD3 antibody is suitable to detect LYPD3 in samples from 人, 小鼠 和 大鼠. It has been validated for ELISA, WB 和 IHC.
产品编号 ABIN8006751
发货至: 中国
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Quick Overview for LYPD3 抗体 (AA 90-392) (HRP) (ABIN8006751)

抗原

See all LYPD3 抗体
LYPD3 (LY6/PLAUR Domain Containing 3 (LYPD3))

适用

  • 34
  • 14
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  • 1
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人, 小鼠, 大鼠

宿主

  • 27
  • 5
  • 1
  • 1
  • 1

克隆类型

  • 27
  • 8
多克隆

标记

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  • 2
  • 2
  • 2
  • 1
  • 1
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This LYPD3 antibody is conjugated to HRP

应用范围

  • 14
  • 12
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ELISA, Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

    • 11
    • 6
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 90-392

    原理

    Anti-LYPD3 Antibody HRP Conjugated

    交叉反应 (详细)

    No cross reactivity with other proteins.

    预测反应

    Human ILKAP shares 98%,98.7% amino acid (aa) sequence identity with mouse,rat ILKAP,respectively.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human ILKAP recombinant protein (Position: E90-H392). Human ILKAP shares 98% and 98.7% amino acid (aa) sequence identity with mouse and rat ILKAP, respectively.

    亚型

    IgG
  • 应用备注

    Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

    有效期

    12 months
  • 抗原

    LYPD3 (LY6/PLAUR Domain Containing 3 (LYPD3))

    别名

    LYPD3

    背景

    Background: Ly6/PLAUR domain-containing protein 3 is a protein that in humans is encoded by the LYPD3 gene. Ly6 / PLAUR domain-containing protein 3, also known as GPI-anchored metastasis-associated protein C4.4A homolog, Matrigel-induced gene C4 protein, MIG-C4, and LYPD3, is a cell membrane protein that contains two UPAR/Ly6 domains. Human LYPD3 contains two UPAR/Ly6 domains. LYPD3 is expressed in the placenta, skin, and urothelium. It is found in suprabasal keratinocytes of chronic wounds. Weak expression of LYPD3 is found in the esophagus and peripheral blood mononuclear cells. It is found in the majority of primary and metastatic transitional cell carcinomas (TCCs) and as well in breast cancer tissues, but not in adjacent normal tissues. High expression of LYPD3 is found in the tumor component of some noninvasive superficial lesions and invasive and metastatic urothelial cancers. LYPD3 is up-regulated in migrating keratinocytes during epithelisation of incisional skin wounds. LYPD3 supports cell migration. It may be involved in urothelial cell-matrix interactions. It may also be involved in tumor progression.

    Gene Full Name: LY6/PLAUR domain containing 3

    基因ID

    27076

    UniProt

    O95274
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