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LIN28B 抗体 (AA 23-249) (Biotin)

This 兔 多克隆 antibody specifically detects LIN28B in WB, ELISA 和 IHC. It exhibits reactivity toward 人.
产品编号 ABIN8006174
发货至: 中国
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北京 101111
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Room 801-803
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Quick Overview for LIN28B 抗体 (AA 23-249) (Biotin) (ABIN8006174)

抗原

See all LIN28B 抗体
LIN28B (Lin-28 Homolog B (LIN28B))

适用

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宿主

  • 69
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克隆类型

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多克隆

标记

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This LIN28B antibody is conjugated to Biotin

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
  • 抗原表位

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    AA 23-249

    原理

    Anti-LIN28B Antibody Biotin Conjugated

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human LIN28B recombinant protein (Position: E23-K249).

    亚型

    IgG
  • 应用备注

    Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

    有效期

    12 months
  • 抗原

    LIN28B (Lin-28 Homolog B (LIN28B))

    别名

    LIN28B

    背景

    Background: The protein encoded by this gene belongs to the lin-28 family, which is characterized by the presence of a cold-shock domain and a pair of CCHC zinc finger domains. This gene is highly expressed in testis, fetal liver, placenta, and in primary human tumors and cancer cell lines. It is negatively regulated by microRNAs that target sites in the 3' UTR, and overexpression of this gene in primary tumors is linked to the repression of let-7 family of microRNAs and derepression of let-7 targets, which facilitates cellular transformation.

    Gene Full Name: lin-28 RNA binding posttranscriptional regulator B

    基因ID

    389421

    UniProt

    Q6ZN17
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