Lrig1 抗体 (AA 79-906) (PE)
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Quick Overview for Lrig1 抗体 (AA 79-906) (PE) (ABIN8005774)
抗原
See all Lrig1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 79-906
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原理
- Anti-LRIG1 Antibody PE Conjugated
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预测反应
- Human LRIG1 shares 89.8% amino acid (aa) sequence identity with mouse LRIG1.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human LRIG1 recombinant protein (Position: K79-E906). Human LRIG1 shares 89.8% amino acid (aa) sequence identity with mouse LRIG1.
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亚型
- IgG
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应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- Lrig1 (Leucine-Rich Repeats and Immunoglobulin-Like Domains 1 (Lrig1))
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别名
- LRIG1
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背景
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Background: Leucine-rich repeats and immunoglobulin-like domains protein 1 is a protein that in humans is encoded by the LRIG1 gene. It is mapped to 3p14.1. Leucine-rich repeats and immunoglobulin-like domains protein 1 is a protein that in humans is encoded by the LRIG1 gene. It encodes a transmembrane protein that has been shown to interact with receptor tyrosine kinases of the EGFR-family, MET and RET. This gene encodes a member of the ATP-dependent DNA ligase protein family. The encoded protein functions in DNA replication, recombination, and the base excision repair process. Mutations in this gene that lead to DNA ligase I deficiency result in immunodeficiency and increased sensitivity to DNA-damaging agents. Disruption of this gene may also be associated with a variety of cancers. Alternative splicing results in multiple transcript variants.
Gene Full Name: leucine rich repeats and immunoglobulin like domains 1
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基因ID
- 26018
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UniProt
- Q96JA1
抗原
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