LMOD3 抗体 (AA 45-558) (Cy3)
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北京 101111
Quick Overview for LMOD3 抗体 (AA 45-558) (Cy3) (ABIN8005303)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 45-558
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原理
- Anti-LMOD3 Antibody Cy3 Conjugated
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交叉反应 （详细）
- No cross-reactivity with other proteins
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预测反应
- Human LMOD3 shares 72.2% amino acid (aa) sequence identity with mouse LMOD3.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human LMOD3 recombinant protein (Position: D45-E558). Human LMOD3 shares 72.2% amino acid (aa) sequence identity with mouse LMOD3.
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亚型
- IgG
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anti-Leiomodin 3 (LMOD3) (AA 45-558) antibody
LMOD3 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Leiomodin 3 (LMOD3) (N-Term) antibodyLMOD3 适用: 人, Cow, 犬, 马 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Flow Cytometry, 1-3 μg/1x106 cells
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- LMOD3 (Leiomodin 3 (LMOD3))
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别名
- LMOD3
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背景
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Background: Leiomodin-3 is a protein that in humans is encoded by the LMOD3 gene. The protein encoded by this gene is a member of the leiomodin family of proteins. This protein contains three actin-binding domains, a tropomyosin domain, a leucine-rich repeat domain, and a Wiskott-Aldrich syndrome protein homology 2 domain (WH2). Localization of this protein to the pointed ends of thin filaments has been observed, and there is evidence that this protein acts as a catalyst of actin nucleation, and is important to the organization of sarcomeric thin filaments in skeletal muscles. Mutations in this gene have been associated as one cause of Nemaline myopathy, as other genes have also been linked to this disorder. Nemaline myopathy is a disorder characterized by nonprogressive generalized muscle weakness and protein inclusions (nemaline bodies) in skeletal myofibers. Patients with mutations in this gene often present with a severe congenital form of the disorder.
Gene Full Name: leiomodin 3
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基因ID
- 56203
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UniProt
- Q0VAK6
抗原
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