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LCAT 抗体 (C-Term) (HRP)

The HRP-conjugated 兔 多克隆 anti-LCAT antibody (ABIN8005177) specifically detects LCAT in WB, IHC 和 ELISA. The antibody is reactive with 人 和 大鼠 samples.
产品编号 ABIN8005177
发货至: 中国
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北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Quick Overview for LCAT 抗体 (C-Term) (HRP) (ABIN8005177)

抗原

See all LCAT 抗体
LCAT (Lecithin-Cholesterol Acyltransferase (LCAT))

适用

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人, 大鼠

宿主

  • 105
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克隆类型

  • 96
  • 21
多克隆

标记

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This LCAT antibody is conjugated to HRP

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA
  • 抗原表位

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    C-Term

    原理

    Anti-LCAT Antibody HRP Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    预测反应

    different from the related rat sequence by two amino acids,and from the mouse sequence by three amino acids.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the C-terminus of human LCAT, different from the related rat sequence by two amino acids, and from the mouse sequence by three amino acids.

    亚型

    IgG
  • 应用备注

    Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

    有效期

    12 months
  • 抗原

    LCAT (Lecithin-Cholesterol Acyltransferase (LCAT))

    别名

    LCAT

    背景

    Background: LCAT (Lecithin: Cholesterol Acyltransferase), is an enzyme that converts free cholesterol into cholesteryl ester. Azoulay et al. (1987) used a cDNA clone corresponding to LCAT to assign the locus to 16q22 through the analysis of DNA from somatic cell hybrids and in situ hybridization. LCAT plays an important role in lipoprotein metabolism, especially in the process termed reverse cholesterol transport The enzyme is synthesized in the liver and circulates in blood plasma as a complex with components of high density lipoprotein (HDL). Cholesterol from peripheral cells is transferred to HDL particles, esterified through the action of LCAT on HDL, and incorporated into the core of the lipoprotein. The cholesterol ester is thereby transported to the liver (Jonas, 2000).

    Gene Full Name: lecithin-cholesterol acyltransferase

    Sequence Similarities: Belongs to the AB hydrolase superfamily. Lipase family.

    基因ID

    3931

    UniProt

    P04180

    途径

    Lipid Metabolism
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