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LCAT 抗体 (C-Term) (APC)

The 兔 多克隆 anti-LCAT antibody is suitable to detect LCAT in samples from 人, 大鼠 和 小鼠. It has been validated for FACS.
产品编号 ABIN8005167
发货至: 中国
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中国
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for LCAT 抗体 (C-Term) (APC) (ABIN8005167)

抗原

See all LCAT 抗体
LCAT (Lecithin-Cholesterol Acyltransferase (LCAT))

适用

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人, 大鼠, 小鼠

宿主

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克隆类型

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多克隆

标记

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This LCAT antibody is conjugated to APC

应用范围

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Flow Cytometry (FACS)
  • 抗原表位

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    C-Term

    原理

    Anti-LCAT Antibody APC Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    预测反应

    different from the related human sequence by six amino acids,and from the related rat sequence by four amino acids.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the C-terminus of mouse LCAT, different from the related human sequence by six amino acids, and from the related rat sequence by four amino acids.

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    LCAT (Lecithin-Cholesterol Acyltransferase (LCAT))

    别名

    Lcat

    背景

    Background: LCAT (Lecithin: Cholesterol Acyltransferase), is an enzyme that converts free cholesterol into cholesteryl ester. Azoulay et al. (1987) used a cDNA clone corresponding to LCAT to assign the locus to 16q22 through the analysis of DNA from somatic cell hybrids and in situ hybridization. LCAT plays an important role in lipoprotein metabolism, especially in the process termed 'reverse cholesterol transport.' The enzyme is synthesized in the liver and circulates in blood plasma as a complex with components of high density lipoprotein (HDL). Cholesterol from peripheral cells is transferred to HDL particles, esterified through the action of LCAT on HDL, and incorporated into the core of the lipoprotein. The cholesterol ester is thereby transported to the liver (Jonas, 2000).

    Gene Full Name: lecithin cholesterol acyltransferase

    Sequence Similarities: Contains 1 HMG box DNA-binding domain.

    基因ID

    16816

    UniProt

    P16301

    途径

    Lipid Metabolism
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