TXNIP 抗体 (AA 101-200)
(2 references)Quick Overview for TXNIP 抗体 (AA 101-200) (ABIN750808)
抗原
See all TXNIP 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 101-200
-
交叉反应
- 人, 小鼠, 大鼠
-
预测反应
- Dog,Pig,Rabbit
-
纯化方法
- Purified by Protein A.
-
免疫原
- KLH conjugated synthetic peptide derived from human TXNIP
-
亚型
- IgG
-
-
anti-Thioredoxin Interacting Protein (TXNIP) (AA 30-381) antibody
TXNIP 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Thioredoxin Interacting Protein (TXNIP) (AA 1-166) antibodyTXNIP 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Thioredoxin Interacting Protein (TXNIP) (AA 32-367) antibodyTXNIP 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Thioredoxin Interacting Protein (TXNIP) (C-Term) antibodyTXNIP 适用: 人, 小鼠, 大鼠, 犬, Cow, 兔, 豚鼠, 绵羊 WB 宿主: 兔 Polyclonal unconjugated
anti-Thioredoxin Interacting Protein (TXNIP) (AA 1-30), (N-Term) antibodyTXNIP 适用: 人 WB 宿主: 兔 Polyclonal RB41554 unconjugated
anti-Thioredoxin Interacting Protein (TXNIP) (AA 116-145) antibodyTXNIP 适用: 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB30652 unconjugated
anti-Thioredoxin Interacting Protein (TXNIP) (Internal Region) antibodyTXNIP 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Thioredoxin Interacting Protein (TXNIP) (C-Term) antibodyTXNIP 适用: 人, 小鼠, 大鼠, 犬, Cow, 兔, 豚鼠, 绵羊, 猴, Bat, Pig, 非洲爪蟾 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Thioredoxin Interacting Protein (TXNIP) (AA 299-381) antibodyTXNIP 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Thioredoxin Interacting Protein (TXNIP) (AA 100-150) antibodyTXNIP 适用: 人, 猴 WB 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 μg/μL
-
缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
-
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
-
有效期
- 12 months
-
-
-
: "Silymarin attenuated paraquat-induced cytotoxicity in macrophage by regulating Trx/TXNIP complex, inhibiting NLRP3 inflammasome activation and apoptosis." in: Toxicology in vitro : an international journal published in association with BIBRA, Vol. 46, pp. 265-272, (2017) (PubMed).
: "MicroRNA-20a negatively regulates expression of NLRP3-inflammasome by targeting TXNIP in adjuvant-induced arthritis fibroblast-like synoviocytes." in: Joint, bone, spine : revue du rhumatisme, Vol. 83, Issue 6, pp. 695-700, (2016) (PubMed).
-
: "Silymarin attenuated paraquat-induced cytotoxicity in macrophage by regulating Trx/TXNIP complex, inhibiting NLRP3 inflammasome activation and apoptosis." in: Toxicology in vitro : an international journal published in association with BIBRA, Vol. 46, pp. 265-272, (2017) (PubMed).
-
- TXNIP (Thioredoxin Interacting Protein (TXNIP))
-
别名
- TXNIP
-
背景
-
Synonyms: THIF, VDUP1, HHCPA78, EST01027, Thioredoxin-interacting protein, Thioredoxin-binding protein 2, Vitamin D3 up-regulated protein 1, TXNIP
Background: May act as an oxidative stress mediator by inhibiting thioredoxin activity or by limiting its bioavailability. Interacts with COPS5 and restores COPS5-induced suppression of CDKN1B stability, blocking the COPS5-mediated translocation of CDKN1B from the nucleus to the cytoplasm. Functions as a transcriptional repressor, possibly by acting as a bridge molecule between transcription factors and corepressor complexes, and over-expression will induce G0/G1 cell cycle arrest. Required for the maturation of natural killer cells. Acts as a suppressor of tumor cell growth. Inhibits the proteasomal degradation of DDIT4, and thereby contributes to the inhibition of the mammalian target of rapamycin complex 1 (mTORC1).
-
基因ID
- 10628
-
UniProt
- Q9H3M7
-
途径
- Protein targeting to Nucleus, Platelet-derived growth Factor Receptor Signaling, Inflammasome
抗原
-
