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KLF6 抗体 (AA 38-205) (Fluoro647)

This 兔 多克隆 antibody specifically detects KLF6 in FACS. It exhibits reactivity toward 人 和 大鼠.
产品编号 ABIN8004773
发货至: 中国
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Quick Overview for KLF6 抗体 (AA 38-205) (Fluoro647) (ABIN8004773)

抗原

See all KLF6 抗体
KLF6 (Kruppel-Like Factor 6 (KLF6))

适用

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人, 大鼠

宿主

  • 50
  • 5

克隆类型

  • 51
  • 4
多克隆

标记

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This KLF6 antibody is conjugated to Fluoro647

应用范围

  • 38
  • 12
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  • 9
  • 6
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  • 1
Flow Cytometry (FACS)
  • 抗原表位

    • 11
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    • 1
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    AA 38-205

    原理

    Anti-KLF6 Antibody Fluoro647 Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    预测反应

    Human KLF6 shares 92%,90% amino acid (aa) sequences identity with mouse,rat KLF6,respectively.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human KLF6 recombinant protein (Position: E38-N205). Human KLF6 shares 92% and 90% amino acid (aa) sequences identity with mouse and rat KLF6, respectively.

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    KLF6 (Kruppel-Like Factor 6 (KLF6))

    别名

    KLF6

    背景

    Background: Krueppel-like factor 6 (KLF6) is a protein that in humans is encoded by the KLF6 gene. It is a tumor suppressor gene which is located on 10p15.1. This gene encodes a nuclear protein that has three zinc fingers at the end of its C-terminal domain, a serine/threonine-rich central region, and an acidic domain lying within the N-terminal region. The zinc fingers of this protein are responsible for the specific DNA binding with the guanine-rich core promoter elements. The central region might be involved in activation or posttranslational regulatory pathways, and the acidic N-terminal domain might play an important role in the process of transcriptional activation. It is capable of activating transcription approximately 4-fold either on homologous or heterologous promoters. The DNA binding and transcriptional activity of this protein, in conjunction with its expression pattern, suggests that this protein may participate in the regulation and/or maintenance of the basal expression of pregnancy-specific glycoprotein genes and possibly other TATA box-less genes.

    Gene Full Name: KLF transcription factor 6

    Sequence Similarities: Belongs to the krueppel C2H2-type zinc-finger protein family.

    基因ID

    1316

    UniProt

    Q99612
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