KLF6 抗体 (AA 38-205) (Fluoro550)
Our Local Distributor
北京 101111
Quick Overview for KLF6 抗体 (AA 38-205) (Fluoro550) (ABIN8004767)
抗原
See all KLF6 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 38-205
-
原理
- Anti-KLF6 Antibody Fluoro550 Conjugated
-
特异性
- No cross reactivity with other proteins.
-
交叉反应 (详细)
- No cross-reactivity with other proteins
-
预测反应
- Human KLF6 shares 92%,90% amino acid (aa) sequences identity with mouse,rat KLF6,respectively.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- E.coli-derived human KLF6 recombinant protein (Position: E38-N205). Human KLF6 shares 92% and 90% amino acid (aa) sequences identity with mouse and rat KLF6, respectively.
-
亚型
- IgG
-
-
-
-
应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
-
有效期
- 12 months
-
-
- KLF6 (Kruppel-Like Factor 6 (KLF6))
-
别名
- KLF6
-
背景
-
Background: Krueppel-like factor 6 (KLF6) is a protein that in humans is encoded by the KLF6 gene. It is a tumor suppressor gene which is located on 10p15.1. This gene encodes a nuclear protein that has three zinc fingers at the end of its C-terminal domain, a serine/threonine-rich central region, and an acidic domain lying within the N-terminal region. The zinc fingers of this protein are responsible for the specific DNA binding with the guanine-rich core promoter elements. The central region might be involved in activation or posttranslational regulatory pathways, and the acidic N-terminal domain might play an important role in the process of transcriptional activation. It is capable of activating transcription approximately 4-fold either on homologous or heterologous promoters. The DNA binding and transcriptional activity of this protein, in conjunction with its expression pattern, suggests that this protein may participate in the regulation and/or maintenance of the basal expression of pregnancy-specific glycoprotein genes and possibly other TATA box-less genes.
Gene Full Name: KLF transcription factor 6
Sequence Similarities: Belongs to the krueppel C2H2-type zinc-finger protein family.
-
基因ID
- 1316
-
UniProt
- Q99612
抗原
-