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KLF5 抗体 (Middle Region) (APC)

The APC-conjugated 兔 多克隆 anti-KLF5 antibody (ABIN8004760) specifically detects KLF5 in FACS. The antibody is reactive with 人 samples.
产品编号 ABIN8004760
发货至: 中国
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Quick Overview for KLF5 抗体 (Middle Region) (APC) (ABIN8004760)

抗原

See all KLF5 抗体
KLF5 (Kruppel-Like Factor 5 (Intestinal) (KLF5))

适用

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宿主

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克隆类型

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多克隆

标记

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This KLF5 antibody is conjugated to APC

应用范围

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Flow Cytometry (FACS)
  • 抗原表位

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    Middle Region

    原理

    Anti-Krueppel-like factor 5 KLF5 Antibody APC Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    预测反应

    identical to the related rat,mouse sequences.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence in the middle region of human KLF5, identical to the related rat and mouse sequences.

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    KLF5 (Kruppel-Like Factor 5 (Intestinal) (KLF5))

    别名

    KLF5

    背景

    Background: KLF5 (Krueppel-like factor 5) is a protein that in humans is encoded by the KLF5 gene. It is also known as BASIC TRANSCRIPTION ELEMENT-BINDING PROTEIN 2 or BTEB2. This gene encodes a member of the Kruppel-like factor subfamily of zinc finger proteins. Suske et al. (2005)stated that the human KLF5 gene maps to chromosome 13q21.33, and the mouse Klf5 gene to chromosome 14E2.1. Sogawa et al. (1993)isolated a cDNA encoding BTEB2. The predicted 219-amino acid protein contains 3 consecutive zinc finger motifs near the C terminus. The zinc finger domains were 59 % and 64 % identical to those of Sp1 (189906) and BTEB1, respectively. Both BTEB2 and Sp1 have a short basic region preceding the zinc finger motifs that may play an auxiliary role in DNA binding. The N-terminal region of BTEB2 is proline rich. Recombinant BTEB2 protein and Sp1 showed very similar DNA-binding specificity in vitro. When expressed in mammalian cells, BTEB2 activated the transcription of a < a href=https://www.bosterbio.com/cells/reporter-cell-lines style=color:#ea8d28>reporter gene fused to a GC box-containing promoter. Sogawa et al. (1993) also identified the rat BTEB2 homolog. Northern blot analysis of rat tissues revealed that BTEB2 is expressed only in the testis and placenta.

    Gene Full Name: KLF transcription factor 5

    Sequence Similarities: Belongs to the krueppel C2H2-type zinc-finger protein family.

    基因ID

    688

    UniProt

    Q13887
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