KRIT1 抗体 (C-Term) (Fluoro488)
Our Local Distributor
北京 101111
Quick Overview for KRIT1 抗体 (C-Term) (Fluoro488) (ABIN8004656)
抗原
See all KRIT1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- C-Term
-
原理
- Anti-KRIT1 Antibody Fluoro488 Conjugated
-
特异性
- No cross reactivity with other proteins.
-
交叉反应 （详细）
- No cross-reactivity with other proteins.
-
预测反应
- different from the related mouse sequence by one amino acid.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human KRIT1, different from the related mouse sequence by one amino acid.
-
亚型
- IgG
-
-
anti-KRIT1, Ankyrin Repeat Containing (KRIT1) (AA 631-736) antibody
KRIT1 适用: 人 WB, IF (cc), IF (p), IHC (fro), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-KRIT1, Ankyrin Repeat Containing (KRIT1) antibodyKD Validated KRIT1 适用: 人 WB, FACS 宿主: 兔 Monoclonal 25GB4350 unconjugated Recombinant Antibody
anti-KRIT1, Ankyrin Repeat Containing (KRIT1) (AA 471-585) antibodyKRIT1 适用: 人 ELISA, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-KRIT1, Ankyrin Repeat Containing (KRIT1) (AA 637-736) antibodyKRIT1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-KRIT1, Ankyrin Repeat Containing (KRIT1) (AA 637-736) antibodyKRIT1 适用: 人 ELISA 宿主: 小鼠 Monoclonal 2C7 unconjugated
anti-KRIT1, Ankyrin Repeat Containing (KRIT1) (AA 637-736) antibodyKRIT1 适用: 人 ELISA 宿主: 小鼠 Monoclonal 1D8 unconjugated
anti-KRIT1, Ankyrin Repeat Containing (KRIT1) (AA 1-736), (N-Term) antibodyKRIT1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
-
有效期
- 12 months
-
-
- KRIT1 (KRIT1, Ankyrin Repeat Containing (KRIT1))
-
别名
- KRIT1
-
背景
-
Background: Krev interaction trapped protein 1 (KRIT1) is a protein that in humans is encoded by the CCM1 gene. This gene encodes a protein containing four ankyrin repeats, a band 4.1/ezrin/radixin/moesin (FERM) domain, and multiple NPXY sequences. The encoded protein is localized in the nucleus and cytoplasm. It binds to integrin cytoplasmic domain-associated protein-1 alpha (ICAP1alpha), and plays a critical role in beta1-integrin-mediated cell proliferation. It associates with junction proteins and RAS-related protein 1A (Rap1A), which requires the encoded protein for maintaining the integrity of endothelial junctions. It is also a microtubule-associated protein and may play a role in microtubule targeting. Mutations in this gene result in cerebral cavernous malformations. Multiple alternatively spliced transcript variants have been found for this gene.
Gene Full Name: KRIT1 ankyrin repeat containing
-
基因ID
- 889
-
UniProt
- O00522
-
途径
- Cell RedoxHomeostasis
抗原
-
