KIF2C 抗体 (AA 531-725) (HRP)
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Quick Overview for KIF2C 抗体 (AA 531-725) (HRP) (ABIN8004483)
抗原
See all KIF2C 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 531-725
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原理
- Anti-MCAK/KIF2C Antibody HRP Conjugated
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特异性
- No cross reactivity with other proteins.
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交叉反应 (详细)
- No cross-reactivity with other proteins
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预测反应
- Human MCAK shares 87% amino acid (aa) sequence identity with both mouse,rat MCAK.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human MCAK recombinant protein (Position: G531-Q725). Human MCAK shares 87% amino acid (aa) sequence identity with both mouse and rat MCAK.
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亚型
- IgG
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应用备注
- Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.
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有效期
- 12 months
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- KIF2C (Kinesin Family Member 2C (KIF2C))
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别名
- KIF2C
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背景
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Background: Kinesin-like protein KIF2C is a protein that in humans is encoded by the KIF2C gene. It is mapped to 1p34.1. The protein encoded by this gene is a member of kinesin-like protein family. Most proteins of this family are microtubule-dependent molecular motors that transport organelles within cells and move chromosomes during cell division. This protein acts to regulate microtubule dynamics in cells and is important for anaphase chromosome segregation and may be required to coordinate the onset of sister centromere separation. KIF2C uses microtubule depolymerizing activity to correct improper microtubule attachments at kinetochores.
Gene Full Name: kinesin family member 2C
Sequence Similarities: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. MCAK/KIF2 subfamily.
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基因ID
- 11004
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UniProt
- Q99661
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途径
- Microtubule Dynamics
抗原
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