Cytokeratin 1 抗体 (AA 223-439) (HRP)
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北京 101111
Quick Overview for Cytokeratin 1 抗体 (AA 223-439) (HRP) (ABIN8004087)
抗原
See all Cytokeratin 1 (KRT1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 223-439
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原理
- Anti-Cytokeratin 1/Krt1 Antibody HRP Conjugated
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived mouse Cytokeratin 1/Krt1 recombinant protein (Position: L223-Q439).
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亚型
- IgG
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应用备注
- Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.
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有效期
- 12 months
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- Cytokeratin 1 (KRT1) (Keratin 1 (KRT1))
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别名
- Krt1
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背景
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Background: Keratin 1 (KRT1), also known as Cytokeratin 1, or Keratin, type II cytoskeletal 1, is a member of the keratin family. It is specifically expressed in the spinous and granular layers of the epidermis with family member keratin 10. Mutations in this gene have been associated with the variants ofbullous congenital ichthyosiform erythroderma in which the palms and soles of the feet are affected. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. And this type II cytokeratin is specifically expressed in the spinous and granular layers of the epidermis with family member KRT10 and mutations in these genes have been associated with bullous congenital ichthyosiform erythroderma. The type II cytokeratins are clustered in a region of chromosome 12q12-q13.
Gene Full Name: keratin 1
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基因ID
- 16678
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UniProt
- P04104
抗原
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