KEAP1 抗体 (AA 25-205) (FITC)
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Quick Overview for KEAP1 抗体 (AA 25-205) (FITC) (ABIN8004053)
抗原
See all KEAP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 25-205
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原理
- Anti-Keap1 Antibody FITC Conjugated
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特异性
- No cross reactivity with other proteins.
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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预测反应
- Human Keap1 shares 96.7%,97.2% amino acid (aa) sequence identity with mouse,rat Keap1,respectively.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human Keap1 recombinant protein (Position: E25-E205). Human Keap1 shares 96.7% and 97.2% amino acid (aa) sequence identity with mouse and rat Keap1, respectively.
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亚型
- IgG
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anti-Kelch-Like ECH-Associated Protein 1 (KEAP1) antibody
KEAP1 适用: 人, 小鼠 WB, IHC, FACS, IHC (p) 宿主: 小鼠 Monoclonal 1B4 unconjugated
anti-Kelch-Like ECH-Associated Protein 1 (KEAP1) (AA 380-624) antibodyKEAP1 适用: 人, 小鼠 ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 1F10B6 unconjugated
anti-Kelch-Like ECH-Associated Protein 1 (KEAP1) (AA 380-624) antibodyKEAP1 适用: 人 IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 7G4B10 unconjugated
anti-Kelch-Like ECH-Associated Protein 1 (KEAP1) (AA 380-624) antibodyKEAP1 适用: 人 WB, IHC, ELISA, FACS 宿主: 小鼠 Monoclonal unconjugated
anti-Kelch-Like ECH-Associated Protein 1 (KEAP1) (AA 65-160) antibodyKEAP1 适用: 人, 小鼠, 大鼠, Pig, 兔 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Kelch-Like ECH-Associated Protein 1 (KEAP1) (AA 327-624) antibodyKEAP1 适用: 人 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Kelch-Like ECH-Associated Protein 1 (KEAP1) (AA 1-286) antibodyKEAP1 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Kelch-Like ECH-Associated Protein 1 (KEAP1) (AA 41-53) antibodyVerified KEAP1 适用: 人 IHC, ELISA, IF 宿主: 山羊 Polyclonal unconjugated
anti-Kelch-Like ECH-Associated Protein 1 (KEAP1) antibodyKD Validated KEAP1 适用: 人 WB, FACS 宿主: 小鼠 Monoclonal 25GB495 unconjugated
anti-Kelch-Like ECH-Associated Protein 1 (KEAP1) (C-Term) antibodyKEAP1 适用: 人, 小鼠, 大鼠, 兔, Cow, 犬, 马, 豚鼠, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- KEAP1 (Kelch-Like ECH-Associated Protein 1 (KEAP1))
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别名
- KEAP1
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背景
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Background: KEAP1 (KELCH-LIKE ECH-ASSOCIATED PROTEIN 1), is a protein that in humans is encoded by the Keap1 gene. The KIAA0132 gene is mapped on 19p13.2. Keap1 contains a central BTB/POZ domain and a C-terminal double glycine repeat (DGR), or Kelch, module. Keap1 has been shown to interact with Nrf2, a master regulator of the antioxidant response, which is important for the amelioration of oxidative stress. In the presence of the electrophilic agent diethylmalate, Nrf2 activity is released from Keap1 and Nrf2 translocate to the nucleus. Under quiescent conditions, Nrf2 is anchored in the cytoplasm through binding to Keap1, which, in turn, facilitates the ubiquitination and subsequent proteolysis of Nrf2. Because Nrf2 activation leads to a coordinated antioxidant and anti-inflammatory response, and Keap1 represses Nrf2 activation, Keap1 has become a very attractive drug target.
Gene Full Name: kelch like ECH associated protein 1
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基因ID
- 9817
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UniProt
- Q14145
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途径
- Maintenance of Protein Location
抗原
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