IDH3B 抗体 (AA 32-362) (FITC)
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北京 101111
Quick Overview for IDH3B 抗体 (AA 32-362) (FITC) (ABIN8003459)
抗原
See all IDH3B 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 32-362
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原理
- Anti-IDH3B Antibody FITC Conjugated
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预测反应
- Human IDH3B shares 97% amino acid (aa) sequence identity with rat IDH3B.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human IDH3B recombinant protein (Position: A32-D362). Human IDH3B shares 97% amino acid (aa) sequence identity with rat IDH3B.
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亚型
- IgG
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应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- IDH3B (Isocitrate Dehydrogenase 3 (NAD+) beta (IDH3B))
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别名
- IDH3B
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背景
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Background: Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial is an enzyme that in humans is encoded by the IDH3B gene. Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit. The protein encoded by this gene is the beta subunit of one isozyme of NAD(+)-dependent isocitrate dehydrogenase. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Gene Full Name: isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit beta
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基因ID
- 3420
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UniProt
- O43837
抗原
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