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IDH3B 抗体 (AA 32-362) (Fluoro550)

The 兔 多克隆 anti-IDH3B antibody is suitable to detect IDH3B in samples from 人, 小鼠 和 大鼠. It has been validated for FACS.
产品编号 ABIN8003457
发货至: 中国
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Room 801-803
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Quick Overview for IDH3B 抗体 (AA 32-362) (Fluoro550) (ABIN8003457)

抗原

See all IDH3B 抗体
IDH3B (Isocitrate Dehydrogenase 3 (NAD+) beta (IDH3B))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

  • 68
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多克隆

标记

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This IDH3B antibody is conjugated to Fluoro550

应用范围

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Flow Cytometry (FACS)
  • 抗原表位

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    AA 32-362

    原理

    Anti-IDH3B Antibody Fluoro550 Conjugated

    预测反应

    Human IDH3B shares 97% amino acid (aa) sequence identity with rat IDH3B.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human IDH3B recombinant protein (Position: A32-D362). Human IDH3B shares 97% amino acid (aa) sequence identity with rat IDH3B.

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    IDH3B (Isocitrate Dehydrogenase 3 (NAD+) beta (IDH3B))

    别名

    IDH3B

    背景

    Background: Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial is an enzyme that in humans is encoded by the IDH3B gene. Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit. The protein encoded by this gene is the beta subunit of one isozyme of NAD(+)-dependent isocitrate dehydrogenase. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene.

    Gene Full Name: isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit beta

    基因ID

    3420

    UniProt

    O43837
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