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ISOC2 抗体 (AA 1-205) (Fluoro550)

This 兔 多克隆 antibody specifically detects ISOC2 in FACS. It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN8003369
发货至: 中国
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Quick Overview for ISOC2 抗体 (AA 1-205) (Fluoro550) (ABIN8003369)

抗原

See all ISOC2 抗体
ISOC2 (Isochorismatase Domain Containing 2 (ISOC2))

适用

人, 小鼠, 大鼠

宿主

  • 27
  • 2

克隆类型

  • 28
多克隆

标记

  • 15
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
This ISOC2 antibody is conjugated to Fluoro550

应用范围

  • 21
  • 15
  • 7
  • 5
  • 3
  • 3
Flow Cytometry (FACS)
  • 抗原表位

    • 14
    • 8
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-205

    原理

    Anti-ISOC2 Antibody Fluoro550 Conjugated

    预测反应

    Human ISOC2 shares 84.2%,75% amino acid (aa) sequence identity with mouse,rat ISOC2,respectively.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human ISOC2 recombinant protein (Position: M1-H205). Human ISOC2 shares 84.2% and 75% amino acid (aa) sequence identity with mouse and rat ISOC2, respectively.

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    ISOC2 (Isochorismatase Domain Containing 2 (ISOC2))

    别名

    ISOC2

    背景

    Background: ISOC2 (isochorismatase domain-containing protein 2) is a 205 amino acid protein belonging to the isochorismatase family. Isochorismatase is an enzyme that catalyzes the chemical reaction of isochorismate and water to 2,3-dihydroxy-2,3-dihydrobenzoate and pyruvate. Localized to mitochondrion and cytoplasm, ISOC2 interacts with CDKN2A and localizes to the nucleus in the presence of it. ISOC2 is ubiquitously expressed, with highest levels found in uterus, stomach and urinary tract system. Over-expressed ISOC2 inhibits the expression of CDKN2A, suggesting that this novel gene may play a role during tumor development by interacting with CDKN2A. Three isoforms are produced by alternative splicing events.

    Gene Full Name: isochorismatase domain containing 2

    基因ID

    79763

    UniProt

    Q96AB3
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