ISOC2 抗体 (AA 1-205) (Biotin)
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Quick Overview for ISOC2 抗体 (AA 1-205) (Biotin) (ABIN8003366)
抗原
See all ISOC2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-205
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原理
- Anti-ISOC2 Antibody Biotin Conjugated
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预测反应
- Human ISOC2 shares 84.2%,75% amino acid (aa) sequence identity with mouse,rat ISOC2,respectively.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human ISOC2 recombinant protein (Position: M1-H205). Human ISOC2 shares 84.2% and 75% amino acid (aa) sequence identity with mouse and rat ISOC2, respectively.
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亚型
- IgG
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anti-Isochorismatase Domain Containing 2 (ISOC2) (AA 1-205) antibody
ISOC2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Isochorismatase Domain Containing 2 (ISOC2) antibodyISOC2 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Isochorismatase Domain Containing 2 (ISOC2) (AA 75-125) antibodyISOC2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Isochorismatase Domain Containing 2 (ISOC2) (AA 159-188), (C-Term) antibodyISOC2 适用: 人 WB 宿主: 兔 Polyclonal RB38463 unconjugated
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应用备注
- Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.
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有效期
- 12 months
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- ISOC2 (Isochorismatase Domain Containing 2 (ISOC2))
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别名
- ISOC2
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背景
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Background: ISOC2 (isochorismatase domain-containing protein 2) is a 205 amino acid protein belonging to the isochorismatase family. Isochorismatase is an enzyme that catalyzes the chemical reaction of isochorismate and water to 2,3-dihydroxy-2,3-dihydrobenzoate and pyruvate. Localized to mitochondrion and cytoplasm, ISOC2 interacts with CDKN2A and localizes to the nucleus in the presence of it. ISOC2 is ubiquitously expressed, with highest levels found in uterus, stomach and urinary tract system. Over-expressed ISOC2 inhibits the expression of CDKN2A, suggesting that this novel gene may play a role during tumor development by interacting with CDKN2A. Three isoforms are produced by alternative splicing events.
Gene Full Name: isochorismatase domain containing 2
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基因ID
- 79763
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UniProt
- Q96AB3
抗原
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