ISL1 抗体 (AA 118-161)
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Quick Overview for ISL1 抗体 (AA 118-161) (ABIN8003332)
抗原
See all ISL1 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
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抗原表位
- AA 118-161
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原理
- Anti-Islet 1/ISL1 Antibody
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交叉反应 (详细)
- No cross reactivity with other proteins.
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预测反应
- Human ISL1 shares 100% amino acid (aa) sequence identity with both mouse,rat ISL1.
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产品特性
- Anti-Islet 1/ISL1 Antibody. Tested in ELISA, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human Islet 1/ISL1 recombinant protein (Position: D118-E161). Human ISL1 shares 100% amino acid (aa) sequence identity with both mouse and rat ISL1.
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亚型
- IgG
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应用备注
- Western blot, 0.25-0.5 μg/mL, Human Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Mouse, Rat Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human Immunofluorescence, 5 μg/mL, Mouse, Rat ELISA, 0.1-0.5 μg/mL, -
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing. -
有效期
- 12 months
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- ISL1 (ISL LIM Homeobox 1 (ISL1))
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别名
- ISL1
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背景
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Background: Insulin gene enhancer protein ISL-1 is a protein that in humans is encoded by the isl1 gene. This gene encodes a member of the LIM/homeodomain family of transcription factors. The encoded protein binds to the enhancer region of the insulin gene, among others, and may play an important role in regulating insulin gene expression. The encoded protein is central to the development of pancreatic cell lineages and may also be required for motor neuron generation. Mutations in this gene have been associated with maturity-onset diabetes of the young.
Gene Full Name: ISL LIM homeobox 1
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分子量
- 42 kDa
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基因ID
- 3670
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UniProt
- P61371
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途径
- Positive Regulation of Peptide Hormone Secretion, Intracellular Steroid Hormone Receptor Signaling Pathway, Peptide Hormone Metabolism, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding, Chromatin Binding
抗原
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