ILF2 抗体 (AA 88-1165)
Our Local Distributor
北京 101111
Quick Overview for ILF2 抗体 (AA 88-1165) (ABIN8002903)
抗原
See all ILF2 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
-
-
抗原表位
- AA 88-1165
-
原理
- Anti-NF45/ILF2 Antibody
-
交叉反应 (详细)
- No cross reactivity with other proteins.
-
预测反应
- Human PC shares 97%,96.6% amino acid (aa) sequence identity with mouse,rat PC,respectively.
-
产品特性
- Anti-NF45/ILF2 Antibody. Tested in ELISA, IF, IHC, ICC, WB, Flow Cytometry applications. This antibody reacts with Human, Monkey, Mouse, Rat.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- E.coli-derived human Pyruvate Carboxylase/PC recombinant protein (Position: R88-D1165). Human PC shares 97% and 96.6% amino acid (aa) sequence identity with mouse and rat PC, respectively.
-
亚型
- IgG
-
-
-
-
应用备注
- Western blot, 0.1-0.25 μg/mL, Human, Monkey, Mouse, Rat Immunohistochemistry (Paraffin-embedded Section), 1-2 μg/mL, Human, Mouse, Rat Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg /1x106 cells, Human ELISA, 0.1-0.5 μg/mL, -
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
-
浓度
- 500 μg/mL
-
缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
-
储存条件
- 4 °C,-20 °C
-
储存方法
-
At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing. -
有效期
- 12 months
-
-
- ILF2 (Interleukin Enhancer Binding Factor 2, 45kDa (ILF2))
-
别名
- ILF2
-
背景
-
Background: Interleukin enhancer-binding factor 2 is a protein that in humans is encoded by the ILF2 gene. The protein encoded by this gene is a transcription factor required for T-cell expression of the interleukin 2 gene. It also binds RNA and is an essential component for encapsidation and protein priming of hepatitis B viral polymerase. The encoded 45 kDa protein (NF45, ILF2) forms a complex with the 90 kDa interleukin enhancer-binding factor 3 (NF90, ILF3), and this complex has been shown to affect the redistribution of nuclear mRNA to the cytoplasm, to repair DNA breaks by nonhomologous end joining, and to negatively regulate the microRNA processing pathway. Knockdown of NF45 or NF90 protein retards cell growth, possibly by inhibition of mRNA stabilization. Alternative splicing results in multiple transcript variants. Related pseudogenes have been found on chromosomes 3 and 14.
Gene Full Name: interleukin enhancer binding factor 2
-
分子量
- 43 kDa
-
基因ID
- 3608
-
UniProt
- Q12905
抗原
-