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IL5RA 抗体 (N-Term) (APC)

The 兔 多克隆 anti-IL5RA antibody is suitable to detect IL5RA in samples from 人. It has been validated for FACS.
产品编号 ABIN8002713
发货至: 中国
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Quick Overview for IL5RA 抗体 (N-Term) (APC) (ABIN8002713)

抗原

See all IL5RA 抗体
IL5RA (Interleukin 5 Receptor, alpha (IL5RA))

适用

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宿主

  • 84
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克隆类型

  • 82
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多克隆

标记

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This IL5RA antibody is conjugated to APC

应用范围

  • 68
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Flow Cytometry (FACS)
  • 抗原表位

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    N-Term

    原理

    Anti-IL5RA Antibody APC Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the N-terminus of human IL5RA.

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    IL5RA (Interleukin 5 Receptor, alpha (IL5RA))

    别名

    IL5RA

    背景

    Background: IL5RA (INTERLEUKIN 5 RECEPTOR, ALPHA), also known as CD125, is a subunit of the Interleukin-5 receptor. IL5RA also denotes its human gene. The protein encoded by this gene is an interleukin 5 specific subunit of a heterodimeric cytokine receptor which is composed of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The IL5RA gene is mapped to 3p26-p24 by Southern blot analysis of DNA from a panel of mouse-human hybrid somatic cell lines complemented by in situ hybridization. And its Cytogenetic location is 3p26.2. Within this 15-residue stretch of IL5RA, the C-terminal phenylalanine is critical. The binding of this protein to IL5 depends on the beta subunit which is activated by the ligand binding and is required for the biological activities of IL5.

    Gene Full Name: interleukin 5 receptor subunit alpha

    Sequence Similarities: Belongs to the type I cytokine receptor family. Type 5 subfamily.

    基因ID

    3568

    UniProt

    Q01344

    途径

    JAK/STAT Signaling
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