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IL2RG 抗体 (Middle Region) (Biotin)

The 兔 多克隆 anti-IL2RG antibody is suitable to detect IL2RG in samples from 人. It has been validated for WB, ELISA 和 IHC.
产品编号 ABIN8002299
发货至: 中国
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北京 101111
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Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for IL2RG 抗体 (Middle Region) (Biotin) (ABIN8002299)

抗原

See all IL2RG 抗体
IL2RG (Interleukin 2 Receptor, gamma (IL2RG))

适用

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宿主

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克隆类型

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多克隆

标记

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This IL2RG antibody is conjugated to Biotin

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
  • 抗原表位

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    Middle Region

    原理

    Anti-IL2 Receptor gamma/IL2RG Antibody Biotin Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence in the middle region of human IL2 Receptor gamma.

    亚型

    IgG
  • 应用备注

    Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

    有效期

    12 months
  • 抗原

    IL2RG (Interleukin 2 Receptor, gamma (IL2RG))

    别名

    IL2RG

    背景

    Background: IL2RG (INTERLEUKIN 2 RECEPTOR, GAMMA),also known as Common gamma chain or CD132, is a cytokine receptor sub-unit that is common to the receptor complexes for at least six different interleukin receptors:IL-2, IL-4, IL-7, IL-9, IL-15 and interleukin-21 receptor. IL2RG is a member of the type I cytokine receptor family expressed on most lymphocyte (white blood cell) populations, and its gene is found on the X-chromosome of mammals. By fluorescence in situ hybridization and PCR amplification of somatic cell hybrid DNAs, The IL2RG gene is mapped to Xq13.1. The IL2RG gene contains 8 exons and spans approximately 4.2 kb. And the gamma chain is an indispensable component of the functional IL2 receptor. Lymphocytes expressing the common gamma chain can form functional receptors for these cytokine proteins, which transmit signals from one cell to another and programs of cellular differentiation. The sharing of the gamma subunit by several receptors explains why humans and mice that lack IL2 entirely show milder symptoms than those with IL2RG deficiency.

    Gene Full Name: interleukin 2 receptor subunit gamma

    Sequence Similarities: Belongs to the type I cytokine receptor family. Type 5 subfamily.

    基因ID

    3561

    UniProt

    P31785

    途径

    JAK/STAT Signaling, Growth Factor Binding
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