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IL12B 抗体 (N-Term) (Fluoro550)

The Fluoro550-conjugated 兔 多克隆 anti-IL12B antibody (ABIN8001796) specifically detects IL12B in FACS. The antibody is reactive with 人 samples.
产品编号 ABIN8001796
发货至: 中国
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Quick Overview for IL12B 抗体 (N-Term) (Fluoro550) (ABIN8001796)

抗原

See all IL12B 抗体
IL12B (Interleukin 12 beta (IL12B))

适用

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宿主

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克隆类型

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多克隆

标记

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This IL12B antibody is conjugated to Fluoro550

应用范围

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Flow Cytometry (FACS)
  • 抗原表位

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    N-Term

    原理

    Anti-IL12 p40/IL12B Antibody Fluoro550 Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the N-terminus of human IL-12(p40).

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    IL12B (Interleukin 12 beta (IL12B))

    别名

    IL12B

    背景

    Background: IL-12, Interleukin 12, heterodimerizes with the IL12 p35 subunit to form IL12 and with the IL23 p19 subunit to form IL23. IL12b p 40 exists as a monomer and as a homodimer. This gene encodes a subunit of Interleukin 12, a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. The IL-12b gene contains 8 exons, the first and last of which are noncoding. By PCR analysis of DNA from rodent/human cell hybrids containing intact chromosomes or translocation chromosomes, the IL-12b gene is mapped to 5q31-q33.This cytokine has been found to be important for sustaining a sufficient number of memory/effector Th1 cells to mediate long-term protection to an intracellular pathogen.

    Gene Full Name: interleukin 12B

    Sequence Similarities: Belongs to the type I cytokine receptor family. Type 3 subfamily.

    基因ID

    3593

    UniProt

    P29460

    途径

    JAK/STAT Signaling, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation
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