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IRF8 抗体 (C-Term) (Biotin)

This 兔 多克隆 antibody specifically detects IRF8 in WB, IHC 和 ELISA. It exhibits reactivity toward 人 和 小鼠.
产品编号 ABIN8001320
发货至: 中国
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Room 801-803
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Quick Overview for IRF8 抗体 (C-Term) (Biotin) (ABIN8001320)

抗原

See all IRF8 抗体
IRF8 (Interferon Regulatory Factor 8 (IRF8))

适用

  • 47
  • 33
  • 13
  • 5
  • 4
  • 4
  • 4
  • 4
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
人, 小鼠

宿主

  • 55
  • 2
  • 1

克隆类型

  • 47
  • 11
多克隆

标记

  • 36
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This IRF8 antibody is conjugated to Biotin

应用范围

  • 39
  • 23
  • 16
  • 16
  • 16
  • 4
  • 4
  • 3
  • 2
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), ELISA
  • 抗原表位

    • 18
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    原理

    Anti-Interferon regulatory factor 8 IRF8 Antibody Biotin Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    预测反应

    different from the related mouse,rat sequences by two amino acids.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the C-terminus of human IRF8, different from the related mouse and rat sequences by two amino acids.

    亚型

    IgG
  • 应用备注

    Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

    有效期

    12 months
  • 抗原

    IRF8 (Interferon Regulatory Factor 8 (IRF8))

    别名

    IRF8

    背景

    Background: Interferon regulatory factor 8 (IRF8) also known as Interferon consensus sequence-binding protein (ICSBP), is a protein that in humans is encoded by the IRF8 gene. By genomic sequence analysis, the IRF8 gene is mapped to chromosome 16q24.1. Interferon consensus sequence-binding protein (ICSBP) is a transcription factor of the interferon (IFN) regulatory factor (IRF) family. The IRF family proteins bind to the IFN-stimulated response element (ISRE) and regulate expression of genes stimulated by type I IFNs, namely IFN-alpha and IFN-beta. IRF family proteins also control expression of IFN-alpha and IFN-beta-regulated genes that are induced by viral infection. IRF8 is a transcription factor that plays critical roles in the regulation of lineage commitment and in myeloid cell maturation including the decision for a common myeloid progenitor (CMP) to differentiate into a monocyte precursor cell.

    Gene Full Name: interferon regulatory factor 8

    Sequence Similarities: Belongs to the IRF family.

    基因ID

    3394

    UniProt

    Q02556

    途径

    Cellular Response to Molecule of Bacterial Origin
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