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IRF2 抗体 (C-Term)

The 兔 多克隆 anti-IRF2 antibody is suitable to detect IRF2 in samples from 人 和 大鼠. It has been validated for WB.
产品编号 ABIN8001120
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for IRF2 抗体 (C-Term) (ABIN8001120)

抗原

See all IRF2 抗体
IRF2 (Interferon Regulatory Factor 2 (IRF2))

适用

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人, 大鼠

宿主

  • 105
  • 5
  • 2

克隆类型

  • 89
  • 23
多克隆

标记

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This IRF2 antibody is un-conjugated

应用范围

  • 72
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  • 5
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Western Blotting (WB)

质量等级

Carrier-free
  • 抗原表位

    • 25
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    C-Term

    原理

    Anti-IRF2 Antibody

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    预测反应

    different from the related mouse sequence by three amino acids.

    产品特性

    Anti-IRF2 Antibody. Tested in WB applications. This antibody reacts with Human, Rat.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the C-terminus of human IRF2, different from the related mouse sequence by three amino acids.

    亚型

    IgG
  • 应用备注

    Western blot, 0.1-0.5 μg/mL, Human, Rat

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, and 0.05 mg Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    IRF2 (Interferon Regulatory Factor 2 (IRF2))

    别名

    IRF2

    背景

    Background: IRF2 (interferon regulatory factor 2) is a member of the interferon regulatory transcription factor (IRF) family. The IRF2 gene is mapped on 4q35.1. When the IRF2 gene was overexpressed in NIH 3T3 cells, the cells became transformed and displayed enhanced tumorigenicity in nude mice. One IRF binding site was found within the IRF2 promoter, and expression of the IRF2 gene was affected by both transient and stable IRF1 expression. IRF2 competitively inhibits the IRF1-mediated transcriptional activation of interferons alpha and beta, and presumably other genes that employ IRF1 for transcription activation. However, IRF2 also functions as a transcriptional activator of histone H4. Irf2 was required to prevent NK-cell apoptosis and keep immature NK cells alive, thus promoting NK-cell maturation and their supply to peripheral blood.

    Gene Full Name: interferon regulatory factor 2

    Sequence Similarities: Contains 1 HMG box DNA-binding domain.

    分子量

    50 kDa

    基因ID

    3660

    UniProt

    P14316
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