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ITGA3 抗体 (N-Term) (Fluoro550)

The 兔 多克隆 anti-ITGA3 antibody is suitable to detect ITGA3 in samples from 人, 小鼠 和 大鼠. It has been validated for FACS.
产品编号 ABIN8000718
发货至: 中国
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Quick Overview for ITGA3 抗体 (N-Term) (Fluoro550) (ABIN8000718)

抗原

See all ITGA3 抗体
ITGA3 (Integrin, alpha 3 (ITGA3))

适用

  • 95
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人, 小鼠, 大鼠

宿主

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  • 25
  • 4
  • 1
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克隆类型

  • 86
  • 28
多克隆

标记

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This ITGA3 antibody is conjugated to Fluoro550

应用范围

  • 63
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Flow Cytometry (FACS)
  • 抗原表位

    • 32
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    N-Term

    原理

    Anti-Integrin alpha 3/ITGA3 Antibody Fluoro550 Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the N-terminus of human Integrin alpha 3, which shares 91.2% amino acid (aa) sequence identity with both mouse and rat Integrin alpha 3.

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    ITGA3 (Integrin, alpha 3 (ITGA3))

    别名

    ITGA3

    背景

    Background: ITGA3 (INTEGRIN, ALPHA-3), also called CD49C, VLA3 or GAPB3, is a protein that in humans is encoded by the ITGA3 gene. It is an integrin alpha subunit which is also a member of the family of cell surface adhesion molecules. This gene is mapped to chromosome 17 and its exact cytogenetic location is 17q21.33. ITGA3 makes up half of the α3β1 integrin duplex that plays a role in neural migration and corticogenesis together with beta-1 subunit.A functional link between DAB1 phosphorylation and ITGA3 signaling drives the timely detachment of migrating neurons from radial glial fibers. Expression of human ITGA3 increased the infectivity of virus for Chinese hamster ovary cells. ITGA3 also contains 13 potential N-glycosylation sites, 2 potential cleavage sites, and the 7 N-terminal repeating units characteristic of ITGAs. Recombinant ITGA3 is expressed as a 150-kD protein as the same size as the native protein by the western blot analysis.

    Gene Full Name: integrin subunit alpha 3

    基因ID

    3675

    UniProt

    P26006

    途径

    CXCR4-mediated Signaling Events, Integrin Complex
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