Integrin beta 4 抗体 (AA 28-266) (PE)
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Quick Overview for Integrin beta 4 抗体 (AA 28-266) (PE) (ABIN8000602)
抗原
See all Integrin beta 4 (ITGB4) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 28-266
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原理
- Anti-Integrin beta 4/ITGB4 Antibody PE Conjugated
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特异性
- No cross reactivity with other proteins.
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交叉反应 （详细）
- No cross-reactivity with other proteins
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预测反应
- Human Integrin beta 4 shares 88%,86% amino acid (aa) sequences identity with mouse,rat Integrin beta 4,respectively.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human Integrin beta 4 recombinant protein (Position: N28-A266). Human Integrin beta 4 shares 88% and 86% amino acid (aa) sequences identity with mouse and rat Integrin beta 4, respectively.
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亚型
- IgG
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anti-Integrin beta 4 (ITGB4) (AA 29-206) antibody
ITGB4 适用: 人 IHC, FACS, ELISA, ICC 宿主: 小鼠 Monoclonal 1D6B4 unconjugated
anti-Integrin beta 4 (ITGB4) (AA 29-206) antibodyITGB4 适用: 人 WB, IHC, FACS, ELISA 宿主: 小鼠 Monoclonal 5G3G5 unconjugated
anti-Integrin beta 4 (ITGB4) (C-Term) antibodyITGB4 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Integrin beta 4 (ITGB4) (AA 1401-1533) antibodyITGB4 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Integrin beta 4 (ITGB4) (AA 29-431) antibodyITGB4 适用: 人, 小鼠, 大鼠 WB, IHC, FACS, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Integrin beta 4 (ITGB4) antibodyKD Validated ITGB4 适用: 人 WB, FACS 宿主: 兔 Monoclonal 25GB7875 unconjugated Recombinant Antibody
anti-Integrin beta 4 (ITGB4) (AA 28-310) antibodyITGB4 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Integrin beta 4 (ITGB4) (AA 28-137) antibodyITGB4 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Integrin beta 4 (ITGB4) antibodyITGB4 适用: 人, 雪貂, Mustelid WB, FACS, IP, IF, IHC (fro) 宿主: 小鼠 Monoclonal 450-9D unconjugated
anti-Integrin beta 4 (ITGB4) (Tyr1510) antibodyITGB4 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- Integrin beta 4 (ITGB4)
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别名
- ITGB4
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背景
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Background: ITGB4 (Integrin, beta-4), also known as CD104 (Cluster of Differentiation 104), is a human gene. The gene encodes the integrin beta 4 subunits, a receptor for the laminins. This subunit tends to associate with alpha 6 subunits and is likely to play a pivotal role in the biology of invasive carcinoma. The ITGB4 gene is mapped on 17q25.1. Using expression profiling, Yang et al. found that ITGB4 was upregulated 6-fold by ZKSCAN3 in transfected human colon cancer cells compared with parental cells. They confirmed that ZKSCAN3 bound the promoter of ITGB4 in vitro and in vivo. ITGB4 knockdown by short hairpin RNA countered ZKSCAN3-augmented anchorage-independent colony formation in the colon cancer cell lines. The integrin beta-4 subunit is characterized by an unusually long cytoplasmic domain that harbors 4 fibronectin type III (FNIII) repeats, residing in 2 pairs separated by a connecting segment. Vidal et al. found compound heterozygosity for mutations in the ITGB4 gene in an infant with junctional epidermolysis bullosa associated with pyloric atresia.
Gene Full Name: integrin subunit beta 4
Sequence Similarities: Belongs to the integrin beta chain family.
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基因ID
- 3691
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UniProt
- P16144
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途径
- Integrin Complex
抗原
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