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IGFBP2 抗体 (C-Term)

The 兔 多克隆 anti-IGFBP2 antibody is suitable to detect IGFBP2 in samples from 人 和 大鼠. It has been validated for WB.
产品编号 ABIN8000142
发货至: 中国
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中国
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for IGFBP2 抗体 (C-Term) (ABIN8000142)

抗原

See all IGFBP2 抗体
IGFBP2 (Insulin-Like Growth Factor Binding Protein 2, 36kDa (IGFBP2))

适用

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人, 大鼠

宿主

  • 117
  • 12
  • 2

克隆类型

  • 99
  • 32
多克隆

标记

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  • 1
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This IGFBP2 antibody is un-conjugated

应用范围

  • 92
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  • 29
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  • 13
  • 9
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  • 3
  • 1
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Western Blotting (WB)

质量等级

Carrier-free
  • 抗原表位

    • 16
    • 15
    • 15
    • 13
    • 8
    • 4
    • 2
    • 2
    • 2
    • 1
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    C-Term

    原理

    Anti-IGFBP2 Antibody

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    预测反应

    different from the related mouse,rat sequences by one amino acid.

    产品特性

    Anti-IGFBP2 Antibody. Tested in WB applications. This antibody reacts with Human, Rat.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the C-terminus of human IGFBP2, different from the related mouse and rat sequences by one amino acid.

    亚型

    IgG
  • 应用备注

    Western blot, 0.1-0.5 μg/mL, Human, Rat

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, and 0.05 mg Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    IGFBP2 (Insulin-Like Growth Factor Binding Protein 2, 36kDa (IGFBP2))

    别名

    IGFBP2

    背景

    Background: The superfamily of insulin-like growth factor (IGF) binding proteins include the six high-affinity IGF binding proteins (IGFBP) and at least four additional low-affinity binding proteins referred to as IGFBP related proteins (IGFBP-rP). All IGFBP superfamily members are cysteine-rich proteins with conserved cysteine residues, which are clustered in the amino- and carboxy-terminal thirds of the molecule. IGFBPs modulate the biological activities of IGF proteins. Some IGFBPs may also have intrinsic bioactivity that is independent of their ability to bind IGF proteins. Post-translational modifications of IGFBPs, including glycosylation, phosphorylation and proteolysis, have been shown to modify the affinities of the binding proteins to IGF. Human IGFBP-2 cDNA encodes a 328 amino acid (aa) residue precursor protein with a putative 39 aa residue signal peptide that is processed to generate the 289 aa residue mature protein. IGFBP-2 contains an integrin receptor recognition sequence (RGD sequence) but lacks potential N-linked glycosylation sites. During development, IGFBP-2 is expressed in a number of tissues. The highest expression level is found in the central nervous system. In adults, high expression levels are also detected in the central nervous system and in a number of reproductive tissues. IGFBP-2 binds preferentially to IGF II, exhibiting a 2-10 fold higher affinity for IGF II than for IGF I.

    Gene Full Name: insulin like growth factor binding protein 2

    Sequence Similarities: Contains 1 IGFBP N-terminal domain.

    分子量

    35 kDa

    基因ID

    3485

    UniProt

    P18065

    途径

    Myometrial Relaxation and Contraction, Growth Factor Binding, Activated T Cell Proliferation
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