IMPA1 抗体 (AA 1-277) (FITC)
Our Local Distributor
北京 101111
Quick Overview for IMPA1 抗体 (AA 1-277) (FITC) (ABIN7999806)
抗原
See all IMPA1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 1-277
-
原理
- Anti-IMPA1 Antibody FITC Conjugated
-
交叉反应 (详细)
- No cross-reactivity with other proteins
-
预测反应
- Human IMPA1 shares 86.6%,85.1% amino acid (aa) sequence identity with mouse,rat IMPA1,respectively.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- E.coli-derived human IMPA1 recombinant protein (Position: M1-D277). Human IMPA1 shares 86.6% and 85.1% amino acid (aa) sequence identity with mouse and rat IMPA1, respectively.
-
亚型
- IgG
-
-
-
-
应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
-
有效期
- 12 months
-
-
- IMPA1 (Inositol(myo)-1(or 4)-Monophosphatase 1 (IMPA1))
-
别名
- IMPA1
-
背景
-
Background: This gene encodes an enzyme that dephosphorylates myo-inositol monophosphate to generate free myo-inositol, a precursor of phosphatidylinositol, and is therefore an important modulator of intracellular signal transduction via the production of the second messengers myoinositol 1,4,5-trisphosphate and diacylglycerol. This enzyme can also use myo-inositol-1,3-diphosphate, myo-inositol-1,4-diphosphate, scyllo-inositol-phosphate, glucose-1-phosphate, glucose-6-phosphate, fructose-1-phosphate, beta-glycerophosphate, and 2'-AMP as substrates. This enzyme shows magnesium-dependent phosphatase activity and is inhibited by therapeutic concentrations of lithium. Inhibition of inositol monophosphate hydroylosis and subsequent depletion of inositol for phosphatidylinositol synthesis may explain the anti-manic and anti-depressive effects of lithium administered to treat bipolar disorder. Alternative splicing results in multiple transcript variants encoding distinct isoforms. A pseudogene of this gene is also present on chromosome 8q21.13.
Gene Full Name: inositol monophosphatase 1
-
基因ID
- 3612
-
UniProt
- P29218
抗原
-