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IMPA1 抗体 (AA 1-277) (Fluoro550)

The Fluoro550-conjugated 兔 多克隆 anti-IMPA1 antibody (ABIN7999804) specifically detects IMPA1 in FACS. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN7999804
发货至: 中国
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Quick Overview for IMPA1 抗体 (AA 1-277) (Fluoro550) (ABIN7999804)

抗原

See all IMPA1 抗体
IMPA1 (Inositol(myo)-1(or 4)-Monophosphatase 1 (IMPA1))

适用

  • 47
  • 26
  • 24
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 42
  • 5

克隆类型

  • 43
  • 4
多克隆

标记

  • 20
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This IMPA1 antibody is conjugated to Fluoro550

应用范围

  • 20
  • 15
  • 10
  • 9
  • 8
  • 5
  • 5
  • 2
  • 2
  • 1
Flow Cytometry (FACS)
  • 抗原表位

    • 23
    • 1
    • 1
    • 1
    • 1
    AA 1-277

    原理

    Anti-IMPA1 Antibody Fluoro550 Conjugated

    交叉反应 (详细)

    No cross-reactivity with other proteins

    预测反应

    Human IMPA1 shares 86.6%,85.1% amino acid (aa) sequence identity with mouse,rat IMPA1,respectively.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human IMPA1 recombinant protein (Position: M1-D277). Human IMPA1 shares 86.6% and 85.1% amino acid (aa) sequence identity with mouse and rat IMPA1, respectively.

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    IMPA1 (Inositol(myo)-1(or 4)-Monophosphatase 1 (IMPA1))

    别名

    IMPA1

    背景

    Background: This gene encodes an enzyme that dephosphorylates myo-inositol monophosphate to generate free myo-inositol, a precursor of phosphatidylinositol, and is therefore an important modulator of intracellular signal transduction via the production of the second messengers myoinositol 1,4,5-trisphosphate and diacylglycerol. This enzyme can also use myo-inositol-1,3-diphosphate, myo-inositol-1,4-diphosphate, scyllo-inositol-phosphate, glucose-1-phosphate, glucose-6-phosphate, fructose-1-phosphate, beta-glycerophosphate, and 2'-AMP as substrates. This enzyme shows magnesium-dependent phosphatase activity and is inhibited by therapeutic concentrations of lithium. Inhibition of inositol monophosphate hydroylosis and subsequent depletion of inositol for phosphatidylinositol synthesis may explain the anti-manic and anti-depressive effects of lithium administered to treat bipolar disorder. Alternative splicing results in multiple transcript variants encoding distinct isoforms. A pseudogene of this gene is also present on chromosome 8q21.13.

    Gene Full Name: inositol monophosphatase 1

    基因ID

    3612

    UniProt

    P29218
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