INPP5D 抗体 (AA 81-1093) (Fluoro488)
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北京 101111
Quick Overview for INPP5D 抗体 (AA 81-1093) (Fluoro488) (ABIN7999759)
抗原
See all INPP5D 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 81-1093
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原理
- Anti-INPP5D Antibody Fluoro488 Conjugated
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交叉反应 （详细）
- No cross reactivity with other proteins.
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预测反应
- Human INPP5D shares 87.6%,87.5% amino acid (aa) sequence identity with mouse,rat INPP5D,respectively.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human INPP5D recombinant protein (Position: Q81-E1093). Human INPP5D shares 87.6% and 87.5% amino acid (aa) sequence identity with mouse and rat INPP5D, respectively.
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亚型
- IgG
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anti-Inositol Polyphosphate-5-Phosphatase, 145kDa (INPP5D) (AA 959-1188) antibody
INPP5D 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Inositol Polyphosphate-5-Phosphatase, 145kDa (INPP5D) (C-Term) antibodyINPP5D 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Inositol Polyphosphate-5-Phosphatase, 145kDa (INPP5D) antibodyINPP5D 适用: 人 WB, ELISA, IHC, IP 宿主: 兔 Monoclonal 9G11 unconjugated Recombinant Antibody
anti-Inositol Polyphosphate-5-Phosphatase, 145kDa (INPP5D) (pTyr1021) antibodyINPP5D 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Inositol Polyphosphate-5-Phosphatase, 145kDa (INPP5D) (N-Term) antibodyINPP5D 适用: 人 WB, ICC, ICFC 宿主: 小鼠 Monoclonal SHIP-01 unconjugated
anti-Inositol Polyphosphate-5-Phosphatase, 145kDa (INPP5D) antibodyINPP5D 适用: 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-Inositol Polyphosphate-5-Phosphatase, 145kDa (INPP5D) (pTyr1021) antibodyINPP5D 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Inositol Polyphosphate-5-Phosphatase, 145kDa (INPP5D) (pTyr1020) antibodyINPP5D 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Inositol Polyphosphate-5-Phosphatase, 145kDa (INPP5D) (AA 770-796) antibodyINPP5D 适用: 人 WB 宿主: 兔 Polyclonal RB17405 unconjugated
anti-Inositol Polyphosphate-5-Phosphatase, 145kDa (INPP5D) (C-Term) antibodyINPP5D 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- INPP5D (Inositol Polyphosphate-5-Phosphatase, 145kDa (INPP5D))
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别名
- INPP5D
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背景
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Background: Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 1 is an enzyme that in humans is encoded by the INPP5D gene. This gene is a member of the inositol polyphosphate-5-phosphatase (INPP5) family and encodes a protein with an N-terminal SH2 domain, an inositol phosphatase domain, and two C-terminal protein interaction domains. Expression of this protein is restricted to hematopoietic cells where its movement from the cytosol to the plasma membrane is mediated by tyrosine phosphorylation. At the plasma membrane, the protein hydrolyzes the 5' phosphate from phosphatidylinositol (3,4,5)-trisphosphate and inositol-1,3,4,5-tetrakisphosphate, thereby affecting multiple signaling pathways. The protein is also partly localized to the nucleus, where it may be involved in nuclear inositol phosphate signaling processes. Overall, the protein functions as a negative regulator of myeloid cell proliferation and survival. Mutations in this gene are associated with defects and cancers of the immune system.
Gene Full Name: inositol polyphosphate-5-phosphatase D
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基因ID
- 3635
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UniProt
- Q92835
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途径
- TCR Signaling, BCR Signaling, Warburg Effect
抗原
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