IDO1 抗体 (N-Term) (Fluoro550)
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北京 101111
Quick Overview for IDO1 抗体 (N-Term) (Fluoro550) (ABIN7999328)
抗原
See all IDO1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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原理
- Anti-Indoleamine 2, 3-dioxygenase/IDO1 Antibody Fluoro550 Conjugated
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特异性
- No cross reactivity with other proteins.
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交叉反应 （详细）
- No cross-reactivity with other proteins
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预测反应
- different from the related mouse sequence by fourteen amino acids,and from the related rat sequence by seventeen amino acids.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the N-terminus of human IDO1, different from the related mouse sequence by fourteen amino acids, and from the related rat sequence by seventeen amino acids.
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亚型
- IgG
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anti-Indoleamine 2,3-Dioxygenase 1 (IDO1) (AA 1-403) antibody
IDO1 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 4D2 unconjugated
anti-Indoleamine 2,3-Dioxygenase 1 (IDO1) (Internal Region) antibodyVerified IDO1 适用: 人 WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Indoleamine 2,3-Dioxygenase 1 (IDO1) (AA 1-403) antibodyIDO1 适用: 人 WB, IHC, ICC, IF (p) 宿主: 兔 Monoclonal BLR031F unconjugated Recombinant Antibody
anti-Indoleamine 2,3-Dioxygenase 1 (IDO1) antibodyIDO1 适用: 人 WB, IHC, IF, IHC (p) 宿主: 小鼠 Monoclonal 1E11 unconjugated
anti-Indoleamine 2,3-Dioxygenase 1 (IDO1) (N-Term) antibodyIDO1 适用: 人 WB, IHC, IF, FACS, ICC 宿主: 兔 Polyclonal unconjugated
anti-Indoleamine 2,3-Dioxygenase 1 (IDO1) (AA 1-403) antibodyIDO1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Indoleamine 2,3-Dioxygenase 1 (IDO1) antibodyIDO1 适用: 小鼠 WB, IHC, ELISA, IF, FACS, IP, FM, MA 宿主: 小鼠 Monoclonal 2E2-6 unconjugated
anti-Indoleamine 2,3-Dioxygenase 1 (IDO1) (AA 1-100) antibodyIDO1 适用: 人 IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Indoleamine 2,3-Dioxygenase 1 (IDO1) (AA 304-403) antibodyIDO1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1C5 unconjugated
anti-Indoleamine 2,3-Dioxygenase 1 (IDO1) (AA 374-403), (C-Term) antibodyIDO1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB15061 unconjugated
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应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- IDO1 (Indoleamine 2,3-Dioxygenase 1 (IDO1))
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别名
- IDO1
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背景
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Background: IDO1 (INDOLEAMINE 2,3-DIOXYGENASE), INDO or IDO, is an immunomodulatory enzyme produced by some alternatively activated macrophages and other immunoregulatory cells. This enzyme catalyzes the degradation of the essential amino acid L-tryptophan to N-formyl-kynurenine. By fluorescence in situ hybridization, the assignment is narrowed to chromosome 8p12-p11. INDO Interferon-gamma has an antiproliferative effect on many tumor cells and inhibits intracellular pathogens such as Toxoplasma and chlamydia, at least partly because of the induction of indoleamine 2,3-dioxygenase. During inflammation, IDO is upregulated in dendritic cells and phagocytes by proinflammatory stimuli, most notably IFNG, and the enzyme then uses superoxide as a 'cofactor' for oxidative cleavage of the indole ring of tryptophan, yielding an intermediate that deformylates to L-kynurenine.
Gene Full Name: indoleamine 2,3-dioxygenase 1
Sequence Similarities: Belongs to the indoleamine 2,3-dioxygenase family.
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基因ID
- 3620
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UniProt
- P14902
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途径
- Activated T Cell Proliferation
抗原
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