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IDS 抗体 (C-Term) (Biotin)

The Biotin-conjugated 兔 多克隆 anti-IDS antibody (ABIN7999049) specifically detects IDS in WB, IHC 和 ELISA. The antibody is reactive with 人 samples.
产品编号 ABIN7999049
发货至: 中国
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Quick Overview for IDS 抗体 (C-Term) (Biotin) (ABIN7999049)

抗原

See all IDS 抗体
IDS (Iduronate 2-Sulfatase (IDS))

适用

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宿主

  • 45
  • 10
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克隆类型

  • 51
  • 7
多克隆

标记

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This IDS antibody is conjugated to Biotin

应用范围

  • 48
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Western Blotting (WB), Immunohistochemistry (IHC), ELISA
  • 抗原表位

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    C-Term

    原理

    Anti-Iduronate 2 sulfatase/IDS Antibody Biotin Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the C-terminus of human Iduronate 2 sulfatase.

    亚型

    IgG
  • 应用备注

    Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

    有效期

    12 months
  • 抗原

    IDS (Iduronate 2-Sulfatase (IDS))

    别名

    IDS

    背景

    Background: IDS (Iduronate-2-sulfatase) is a sulfatase enzyme associated with Hunter syndrome. Iduronate 2-sulfatase is involved in the lysosomal degradation of the glycosaminoglycans heparan sulfate and dermatan sulfate. Wilson et al. (1991) used an IDS cDNA clone to localize the gene to Xq28, distal to the fragile X site. Faust et al. (1992) and Daniele et al. (1993) demonstrated that the homologous Ids gene in the mouse occupies the same position on the X chromosome in relation to the FMR1, F9, and GABRA3 genes. Iduronate-2-sulfatase is required for the lysosomal degradation of heparan sulfate and dermatan sulfate. Mutations in this X-chromosome gene that result in enzymatic deficiency lead to the sex-linked mucopolysaccharidosis type II, also known as Hunter syndrome. Iduronate-2-sulfatase has a strong sequence homology with human arylsulfatases A, B, and C, and human glucosamine-6-sulfatase.

    Gene Full Name: iduronate 2-sulfatase

    Sequence Similarities: Contains 2 follistatin-like domains.

    基因ID

    3423

    UniProt

    P22304

    途径

    Glycosaminoglycan Metabolic Process
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