HYOU1 抗体 (AA 46-913) (HRP)
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北京 101111
Quick Overview for HYOU1 抗体 (AA 46-913) (HRP) (ABIN7999033)
抗原
See all HYOU1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 46-913
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原理
- Anti-ORP150/HYOU1 Antibody HRP Conjugated
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human ORP150/HYOU1 recombinant protein (Position: K46-K913).
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亚型
- IgG
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anti-Hypoxia Up Regulated 1 (HYOU1) (C-Term) antibody
HYOU1 适用: 人 WB, ICC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Hypoxia Up Regulated 1 (HYOU1) (AA 901-999) antibodyHYOU1 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 6F7 unconjugated
anti-Hypoxia Up Regulated 1 (HYOU1) (AA 46-913) antibodyHYOU1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Hypoxia Up Regulated 1 (HYOU1) (C-Term) antibodyHYOU1 适用: 人, 大鼠 WB, IHC, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Hypoxia Up Regulated 1 (HYOU1) (AA 401-500) antibodyHYOU1 适用: 人, 小鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Hypoxia Up Regulated 1 (HYOU1) (AA 695-994) antibodyHYOU1 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Hypoxia Up Regulated 1 (HYOU1) antibodyHYOU1 适用: 人 WB, ICC, IF 宿主: 小鼠 Monoclonal 6E3-2C3 unconjugated
anti-Hypoxia Up Regulated 1 (HYOU1) antibody (Atto 594)HYOU1 适用: 人 WB, ICC, IF 宿主: 小鼠 Monoclonal 6E3-2C3 Atto 594
anti-Hypoxia Up Regulated 1 (HYOU1) antibody (Atto 390)HYOU1 适用: 人 WB, ICC, IF 宿主: 小鼠 Monoclonal 6E3-2C3 Atto 390
anti-Hypoxia Up Regulated 1 (HYOU1) antibody (Atto 488)HYOU1 适用: 人 WB, ICC, IF 宿主: 小鼠 Monoclonal 6E3-2C3 Atto 488
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应用备注
- Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.
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有效期
- 12 months
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- HYOU1 (Hypoxia Up Regulated 1 (HYOU1))
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别名
- HYOU1
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背景
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Background: Hypoxia up-regulated protein 1 is a protein that in humans is encoded by the HYOU1 gene. The protein encoded by this gene belongs to the heat shock protein 70 family. This gene uses alternative transcription start sites. A cis-acting segment found in the 5' UTR is involved in stress-dependent induction, resulting in the accumulation of this protein in the endoplasmic reticulum (ER) under hypoxic conditions. The protein encoded by this gene is thought to play an important role in protein folding and secretion in the ER. Since suppression of the protein is associated with accelerated apoptosis, it is also suggested to have an important cytoprotective role in hypoxia-induced cellular perturbation. This protein has been shown to be up-regulated in tumors, especially in breast tumors, and thus it is associated with tumor invasiveness. This gene also has an alternative translation initiation site, resulting in a protein that lacks the N-terminal signal peptide. This signal peptide-lacking protein, which is only 3 amino acids shorter than the mature protein in the ER, is thought to have a housekeeping function in the cytosol. In rat, this protein localizes to both the ER by a carboxy-terminal peptide sequence and to mitochondria by an amino-terminal targeting signal. Alternative splicing results in multiple transcript variants.
Gene Full Name: hypoxia up-regulated 1
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基因ID
- 10525
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UniProt
- Q9Y4L1
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途径
- ER-Nucleus Signaling, SARS-CoV-2 Protein Interactome
抗原
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