HSD17B8 抗体 (AA 42-244) (APC)
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Quick Overview for HSD17B8 抗体 (AA 42-244) (APC) (ABIN7998880)
抗原
See all HSD17B8 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 42-244
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原理
- Anti-HSD17B8 Antibody APC Conjugated
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human HSD17B8 recombinant protein (Position: D42-D244).
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亚型
- IgG
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应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- HSD17B8 (Hydroxysteroid (17-Beta) Dehydrogenase 8 (HSD17B8))
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别名
- HSD17B8
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背景
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Background: Estradiol 17 beta-dehydrogenase 8 is an enzyme that in humans is encoded by the HSD17B8 gene. In mice, the Ke6 protein is a 17-beta-hydroxysteroid dehydrogenase that can regulate the concentration of biologically active estrogens and androgens. It is preferentially an oxidative enzyme and inactivates estradiol, testosterone, and dihydrotestosterone. However, the enzyme has some reductive activity and can synthesize estradiol from estrone. The protein encoded by this gene is similar to Ke6 and is a member of the short-chain dehydrogenase superfamily. An alternatively spliced transcript of this gene has been detected, but the full-length nature of this variant has not been determined.
Gene Full Name: hydroxysteroid 17-beta dehydrogenase 8
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基因ID
- 7923
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UniProt
- Q92506
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途径
- Steroid Hormone Biosynthesis
抗原
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