HSD17B1 抗体 (N-Term) (FITC)
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Quick Overview for HSD17B1 抗体 (N-Term) (FITC) (ABIN7998757)
抗原
See all HSD17B1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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原理
- Anti-HSD17B1 Antibody FITC Conjugated
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特异性
- No cross reactivity with other proteins.
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交叉反应 （详细）
- No cross-reactivity with other proteins
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预测反应
- different from the related rat,mouse sequences by one amino acid.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the N-terminus of human HSD17B1, different from the related rat and mouse sequences by one amino acid.
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亚型
- IgG
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anti-Hydroxysteroid (17-Beta) Dehydrogenase 1 (HSD17B1) (AA 189-285) antibody
HSD17B1 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 2E5 unconjugated
anti-Hydroxysteroid (17-Beta) Dehydrogenase 1 (HSD17B1) (N-Term) antibodyHSD17B1 适用: 人, 大鼠 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Hydroxysteroid (17-Beta) Dehydrogenase 1 (HSD17B1) antibodyHSD17B1 适用: 人, 大鼠, 小鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Hydroxysteroid (17-Beta) Dehydrogenase 1 (HSD17B1) (AA 29-43) antibodyHSD17B1 适用: 人, 大鼠 WB, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Hydroxysteroid (17-Beta) Dehydrogenase 1 (HSD17B1) (AA 21-120) antibodyHSD17B1 适用: 人, 小鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Hydroxysteroid (17-Beta) Dehydrogenase 1 (HSD17B1) (AA 4-289) antibodyHSD17B1 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Hydroxysteroid (17-Beta) Dehydrogenase 1 (HSD17B1) (AA 268-328) antibodyHSD17B1 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Hydroxysteroid (17-Beta) Dehydrogenase 1 (HSD17B1) (N-Term) antibodyHSD17B1 适用: 人, 大鼠, 小鼠, Cow, 犬, 马, Pig WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Hydroxysteroid (17-Beta) Dehydrogenase 1 (HSD17B1) (N-Term) antibodyHSD17B1 适用: 人, 大鼠, 小鼠, Cow, 犬, 马, Pig, 豚鼠, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Hydroxysteroid (17-Beta) Dehydrogenase 1 (HSD17B1) (C-Term) antibodyHSD17B1 适用: 人 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- HSD17B1 (Hydroxysteroid (17-Beta) Dehydrogenase 1 (HSD17B1))
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别名
- HSD17B1
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背景
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Background: Estradiol 17-beta-dehydrogenase 1 is an enzyme that in humans is encoded by the HSD17B1 gene. This gene encodes a member of the 17beta-hydroxysteroid dehydrogenase family of short-chain dehydrogenases/reductases. It has a dual function in estrogen activation and androgen inactivation and plays a major role in establishing the estrogen E2 concentration gradient between serum and peripheral tissues. The encoded protein catalyzes the last step in estrogen activation, using NADPH to convert estrogens E1 and E2 and androgens like 4-androstenedione, to testosterone. It has an N-terminal short-chain dehydrogenase domain with a cofactor binding site, and a narrow, hydrophobic C-terminal domain with a steroid substrate binding site. This gene is expressed primarily in the placenta and ovarian granulosa cells, and to a lesser extent, in the endometrium, adipose tissue, and prostate. Polymorphisms in this gene have been linked to breast and prostate cancer. A pseudogene of this gene has been identified. Alternative splicing results in multiple transcript variants.
Gene Full Name: hydroxysteroid 17-beta dehydrogenase 1
Sequence Similarities: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
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基因ID
- 3292
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UniProt
- P14061
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途径
- Metabolism of Steroid Hormones and Vitamin D, Steroid Hormone Biosynthesis
抗原
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