Huntingtin 抗体 (AA 3079-3142) (Biotin)
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Quick Overview for Huntingtin 抗体 (AA 3079-3142) (Biotin) (ABIN7998422)
抗原
See all Huntingtin (HTT) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 3079-3142
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原理
- Anti-Huntingtin/HTT Antibody Biotin Conjugated
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交叉反应 （详细）
- No cross reactivity with other proteins.
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预测反应
- Human HTT shares 93.8%,92.2% amino acid (aa) sequence identity with mouse,rat HTT,respectively.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human Huntingtin/HTT recombinant protein (Position: R3079-C3142). Human HTT shares 93.8% and 92.2% amino acid (aa) sequence identity with mouse and rat HTT, respectively.
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亚型
- IgG
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anti-Huntingtin (HTT) antibody
KD Validated HTT 适用: 人 WB, ICC, FACS, IF (p) 宿主: 兔 Monoclonal 23GB6285 unconjugated Recombinant Antibody
anti-Huntingtin (HTT) antibodyHTT 适用: 人 IHC, WB, IF 宿主: 兔 Monoclonal unconjugated
anti-Huntingtin (HTT) (AA 81-190) antibodyHTT 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 3F1 unconjugated
anti-Huntingtin (HTT) (AA 81-190) antibodyHTT 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2E10 unconjugated
anti-Huntingtin (HTT) (AA 85-200) antibodyHTT 适用: 人, 大鼠, 小鼠, 兔, 猴, 马, 犬, 绵羊, Pig, Hamster, 豚鼠, 山羊, 驴, Cow, 小鸡, Cat, Avian WB, IF, IHC (p), IHC (fro) 宿主: 山羊 Polyclonal unconjugated
anti-Huntingtin (HTT) (AA 81-190) antibodyHTT 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1H6 unconjugated
anti-Huntingtin (HTT) (AA 782-920) antibodyHTT 适用: 小鼠 IHC, WB, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Huntingtin (HTT) (AA 81-190) antibodyHTT 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3F9 unconjugated
anti-Huntingtin (HTT) (AA 81-191) antibodyHTT 适用: 人 IHC, WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 3F1 unconjugated
anti-Huntingtin (HTT) antibodyHTT 适用: 人 IHC, ELISA 宿主: 兔 Monoclonal 6F2 unconjugated Recombinant Antibody
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应用备注
- Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.
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有效期
- 12 months
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- Huntingtin (HTT)
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别名
- HTT
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背景
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Background: The huntingtin gene, also called HTT or HD(Huntington disease) gene, is the IT15(interesting transcript 15) gene which codes for a protein called the huntingtin protein. It is mapped to 4p16.3. The protein has no sequence homology with other proteins and is highly expressed in neurons and tests in humans and rodents. HTT upregulates the expression of Brain Derived Neurotrophic Factor(BDNF) at the transcription level, and this gene is required for normal development. The HTT protein is involved in vesicle trafficking as it interacts with HIP1, a clathrin-binding protein, to mediate endocytosis, the absorption of materials into a cell. HTT was also visualized as punctate staining likely to represent nerve endings. What's more, wildtype HTT may function in the nucleus in the assembly of nuclear matrix-bound protein complexes involved with transcriptional repression and RNA processing.
Gene Full Name: huntingtin
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基因ID
- 3064
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UniProt
- P42858
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途径
- PI3K-Akt Signaling, Hormone Transport, Transition Metal Ion Homeostasis, Tube Formation, Protein targeting to Nucleus, Dicarboxylic Acid Transport
抗原
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