HTRA2 抗体 (AA 30-458)
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北京 101111
Quick Overview for HTRA2 抗体 (AA 30-458) (ABIN7998399)
抗原
See all HTRA2 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
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抗原表位
- AA 30-458
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原理
- Anti-HTRA2 Antibody
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交叉反应 (详细)
- No cross reactivity with other proteins.
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预测反应
- Human HTRA2 shares 85.7% amino acid (aa) sequence identity with mouse HTRA2.
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产品特性
- Anti-HTRA2 Antibody. Tested in ELISA, IF, IHC, ICC, WB, Flow Cytometry applications. This antibody reacts with Human.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human HTRA2 recombinant protein (Position: R30-E458). Human HTRA2 shares 85.7% amino acid (aa) sequence identity with mouse HTRA2.
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亚型
- IgG
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应用备注
- Western blot, 0.25-0.5 μg/mL, Human Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human ELISA, 0.1-0.5 μg/mL, -
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing. -
有效期
- 12 months
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- HTRA2 (HtrA Serine Peptidase 2 (HTRA2))
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别名
- HTRA2
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背景
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Background: Serine protease HTRA2, mitochondrial is an enzyme that in humans is encoded by the HTRA2 gene. This gene encodes a serine protease. The protein has been localized in the endoplasmic reticulum and interacts with an alternatively spliced form of mitogen-activated protein kinase 14. The protein has also been localized to the mitochondria with release to the cytosol following apoptotic stimulus. The protein is thought to induce apoptosis by binding the apoptosis inhibitory protein baculoviral IAP repeat-containing 4. Nuclear localization of this protein has also been observed. Alternate splicing of this gene results in multiple transcript variants encoding different isoforms.
Gene Full Name: HtrA serine peptidase 2
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分子量
- 36 kDa
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基因ID
- 27429
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UniProt
- O43464
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途径
- Positive Regulation of Endopeptidase Activity
抗原
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