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HDAC4 抗体 (AA 4-213) (APC)

This 兔 多克隆 antibody specifically detects HDAC4 in FACS. It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN7997790
发货至: 中国
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Quick Overview for HDAC4 抗体 (AA 4-213) (APC) (ABIN7997790)

抗原

See all HDAC4 抗体
HDAC4 (Histone Deacetylase 4 (HDAC4))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This HDAC4 antibody is conjugated to APC

应用范围

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Flow Cytometry (FACS)
  • 抗原表位

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    AA 4-213

    原理

    Anti-HDAC4 Antibody APC Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    预测反应

    Human HDAC4 shares 98.6%,98.1% amino acid (aa) sequence identity with mouse,rat HDAC4,respectively.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human HDAC4 recombinant protein (Position: Q4-Q213). Human HDAC4 shares 98.6% and 98.1% amino acid (aa) sequence identity with mouse and rat HDAC4, respectively.

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    HDAC4 (Histone Deacetylase 4 (HDAC4))

    别名

    HDAC4

    背景

    Background: Histone deacetylase 4, also known as HDAC4, is a protein that in humans is encoded by the HDAC4 gene. It is mapped to 2q37.3. Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA ly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3.

    Gene Full Name: histone deacetylase 4

    基因ID

    9759

    UniProt

    P56524

    途径

    Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process
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