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HDAC11 抗体 (N-Term) (APC)

The APC-conjugated 兔 多克隆 anti-HDAC11 antibody (ABIN7997735) specifically detects HDAC11 in FACS. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN7997735
发货至: 中国
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Quick Overview for HDAC11 抗体 (N-Term) (APC) (ABIN7997735)

抗原

See all HDAC11 抗体
HDAC11 (Histone Deacetylase 11 (HDAC11))

适用

  • 66
  • 51
  • 18
  • 3
  • 3
  • 3
  • 3
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  • 1
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人, 小鼠, 大鼠

宿主

  • 70
  • 6

克隆类型

  • 61
  • 15
多克隆

标记

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  • 4
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  • 1
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This HDAC11 antibody is conjugated to APC

应用范围

  • 65
  • 30
  • 26
  • 12
  • 8
  • 7
  • 4
  • 3
  • 2
  • 1
  • 1
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Flow Cytometry (FACS)
  • 抗原表位

    • 15
    • 9
    • 8
    • 8
    • 7
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    原理

    Anti-HDAC11 Antibody APC Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    预测反应

    different from the related mouse sequence by one amino acid.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the N-terminus of human HDAC11, different from the related mouse sequence by one amino acid.

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    HDAC11 (Histone Deacetylase 11 (HDAC11))

    别名

    HDAC11

    背景

    Background: Histone deacetylase 11 is a 39 kDa histone deacetylase enzyme that in humans is encoded by the HDAC11 gene on chromosome 3 in humans and chromosome 6 in mice. This gene encodes a class IV histone deacetylase. And the encoded protein is localized to the nucleus and may be involved in regulating the expression of interleukin 10. Alternative splicing results in multiple transcript variants. HDAC11 expression is normally found in brain and testis tissue, but upregulation of HDAC11 expression has also been seen in various cancer cells. In addition, HDAC11 has been shown to be a negative regulator of IL-10 production in antigen presenting cells. It has also been shown that inhibition of HDAC11 results in increased expression of OX40L in Hodgkin lymphoma cells.

    Gene Full Name: histone deacetylase 11

    Sequence Similarities: Contains 1 HMG box DNA-binding domain.

    基因ID

    79885

    UniProt

    Q96DB2
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