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HRH3 抗体 (C-Term) (Cy3)

The Cy3-conjugated 兔 多克隆 anti-HRH3 antibody (ABIN7997630) specifically detects HRH3 in FACS. The antibody is reactive with 人, 大鼠 和 小鼠 samples.
产品编号 ABIN7997630
发货至: 中国
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Quick Overview for HRH3 抗体 (C-Term) (Cy3) (ABIN7997630)

抗原

See all HRH3 抗体
HRH3 (Histamine Receptor H3 (HRH3))

适用

  • 107
  • 69
  • 57
  • 5
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  • 1
人, 大鼠, 小鼠

宿主

  • 107
  • 3
  • 1

克隆类型

  • 95
  • 16
多克隆

标记

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  • 1
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  • 1
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This HRH3 antibody is conjugated to Cy3

应用范围

  • 82
  • 26
  • 21
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  • 17
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  • 13
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  • 6
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  • 3
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Flow Cytometry (FACS)
  • 抗原表位

    • 20
    • 15
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    • 8
    • 5
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    • 2
    • 1
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    C-Term

    原理

    Anti-Histamine H3 receptor HRH3 Antibody Cy3 Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    预测反应

    different from the related rat sequence by three amino acids.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the C-terminus of human HRH3, different from the related rat sequence by three amino acids.

    亚型

    IgG
  • 应用备注

    Flow Cytometry, 1-3 μg/1x106 cells

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    HRH3 (Histamine Receptor H3 (HRH3))

    别名

    HRH3

    背景

    Background: The histamine receptor H3 (HRH3) is a presynaptic autoreceptor on histamine neurons in the brain and a presynaptic heteroreceptor in nonhistamine-containing neurons in both the central and peripheral nervous systems. The deduced 445-amino acid HRH3 protein contains 7 predicted transmembrane domains. And it shares 22 % and 21.4 % amino acid sequence homology with the H1 (HRH1) and H2 (HRH2) receptors, respectively. The expression of recombinant HRH3 in a variety of cell lines conferred an ability to inhibit adenylate cyclase in response to histamine, but not to acetylcholine or any other biogenic amine. Additionally, HRH3 was most notably observed throughout the thalamus, the ventromedial hypothalamus, and the caudate nucleus. Strong expression was also seen in layers II, V, and VIb of the cerebral cortex, in the pyramidal layers of the hippocampus, and in olfactory tubercle.

    Gene Full Name: histamine receptor H3

    基因ID

    11255

    UniProt

    Q9Y5N1

    途径

    cAMP Metabolic Process, Feeding Behaviour
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