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ChT 抗体 (AA 446-580) (HRP)

The HRP-conjugated 兔 多克隆 anti-ChT antibody (ABIN7997525) specifically detects ChT in WB, IHC 和 ELISA. The antibody is reactive with 小鼠, 人 和 大鼠 samples.
产品编号 ABIN7997525
发货至: 中国
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Quick Overview for ChT 抗体 (AA 446-580) (HRP) (ABIN7997525)

抗原

See all ChT 抗体
ChT (High Affinity Choline Transporter (ChT))

适用

  • 24
  • 22
  • 22
  • 9
  • 4
  • 4
  • 4
  • 4
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
小鼠, 人, 大鼠

宿主

  • 23
  • 9
  • 1

克隆类型

  • 24
  • 9
多克隆

标记

  • 18
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This ChT antibody is conjugated to HRP

应用范围

  • 19
  • 15
  • 7
  • 6
  • 5
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), ELISA
  • 抗原表位

    • 12
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 446-580

    原理

    Anti-SLC5A7 Antibody HRP Conjugated

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human SLC5A7 recombinant protein (Position: R446-Q580).

    亚型

    IgG
  • 应用备注

    Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

    有效期

    12 months
  • 抗原

    ChT (High Affinity Choline Transporter (ChT))

    别名

    SLC5A7

    背景

    Background: The high-affinity choline transporter (ChT) also known as solute carrier family 5 member 7 is a protein in humans that is encoded by the SLC5A7 gene. This gene encodes a sodium ion- and chloride ion-dependent high-affinity transporter that mediates choline uptake for acetylcholine synthesis in cholinergic neurons. The protein transports choline from the extracellular space into presynaptic terminals for synthesis into acetylcholine. Increased choline uptake results from increased density of this protein in synaptosomal plasma membranes in response to depolarization of cholinergic terminals. Dysfunction of cholinergic signaling has been implicated in various disorders including depression, attention-deficit disorder, and schizophrenia. An allelic variant of this gene is associated with autosomal dominant distal hereditary motor neuronopathy type VIIA. Alternative splicing results in multiple transcript variants.

    Gene Full Name: solute carrier family 5 member 7

    基因ID

    60482

    UniProt

    Q9GZV3
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