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HEXB 抗体 (AA 381-556) (APC)

The 兔 多克隆 anti-HEXB antibody is suitable to detect HEXB in samples from 人. It has been validated for FACS.
产品编号 ABIN7997515
发货至: 中国
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Quick Overview for HEXB 抗体 (AA 381-556) (APC) (ABIN7997515)

抗原

See all HEXB 抗体
HEXB (Hexosaminidase B (Beta Polypeptide) (HEXB))

适用

  • 49
  • 11
  • 6

宿主

  • 48
  • 10

克隆类型

  • 50
  • 8
多克隆

标记

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  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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This HEXB antibody is conjugated to APC

应用范围

  • 33
  • 31
  • 15
  • 9
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  • 3
  • 2
  • 1
Flow Cytometry (FACS)
  • 抗原表位

    • 11
    • 6
    • 5
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    • 2
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    • 1
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    AA 381-556

    原理

    Anti-HEXB Antibody APC Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    预测反应

    Human HEXB shares 75%,73% amino acid (aa) sequences identity with mouse,rat HEXB,respectively.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human HEXB recombinant protein (Position: K381-M556). Human HEXB shares 75% and 73% amino acid (aa) sequences identity with mouse and rat HEXB, respectively.

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    HEXB (Hexosaminidase B (Beta Polypeptide) (HEXB))

    别名

    HEXB

    背景

    Background: Beta-hexosaminidase subunit beta (HEXB) is an enzyme that in humans is encoded by the HEXB gene. It is mapped to 5q13.3. HEXB is the beta subunit of the lysosomal enzyme beta-hexosaminidase that, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Beta subunit gene mutations lead to Sandhoff disease (GM2-gangliosidosis type II). It has been found that HEXB is a peptidoglycan hydrolase and it is involved in restricting mycobacteria growth even before the onset of adaptive immunity.

    Gene Full Name: hexosaminidase subunit beta

    Sequence Similarities: Belongs to the glycosyl hydrolase 20 family.

    基因ID

    3074

    UniProt

    P07686

    途径

    Sensory Perception of Sound, Glycosaminoglycan Metabolic Process
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