HEXB 抗体 (AA 381-556) (APC)
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Quick Overview for HEXB 抗体 (AA 381-556) (APC) (ABIN7997515)
抗原
See all HEXB 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 381-556
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原理
- Anti-HEXB Antibody APC Conjugated
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特异性
- No cross reactivity with other proteins.
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交叉反应 (详细)
- No cross-reactivity with other proteins
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预测反应
- Human HEXB shares 75%,73% amino acid (aa) sequences identity with mouse,rat HEXB,respectively.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human HEXB recombinant protein (Position: K381-M556). Human HEXB shares 75% and 73% amino acid (aa) sequences identity with mouse and rat HEXB, respectively.
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亚型
- IgG
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应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- HEXB (Hexosaminidase B (Beta Polypeptide) (HEXB))
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别名
- HEXB
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背景
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Background: Beta-hexosaminidase subunit beta (HEXB) is an enzyme that in humans is encoded by the HEXB gene. It is mapped to 5q13.3. HEXB is the beta subunit of the lysosomal enzyme beta-hexosaminidase that, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Beta subunit gene mutations lead to Sandhoff disease (GM2-gangliosidosis type II). It has been found that HEXB is a peptidoglycan hydrolase and it is involved in restricting mycobacteria growth even before the onset of adaptive immunity.
Gene Full Name: hexosaminidase subunit beta
Sequence Similarities: Belongs to the glycosyl hydrolase 20 family.
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基因ID
- 3074
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UniProt
- P07686
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途径
- Sensory Perception of Sound, Glycosaminoglycan Metabolic Process
抗原
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