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HAVCR1 抗体 (AA 58-289) (FITC)

The 兔 多克隆 anti-HAVCR1 antibody is suitable to detect HAVCR1 in samples from 人, 小鼠 和 大鼠. It has been validated for FACS.
产品编号 ABIN7997083
发货至: 中国
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Quick Overview for HAVCR1 抗体 (AA 58-289) (FITC) (ABIN7997083)

抗原

See all HAVCR1 抗体
HAVCR1 (Hepatitis A Virus Cellular Receptor 1 (HAVCR1))

适用

  • 140
  • 64
  • 57
  • 6
  • 5
  • 4
  • 1
人, 小鼠, 大鼠

宿主

  • 155
  • 28
  • 8
  • 3
  • 2

克隆类型

  • 151
  • 40
  • 4
多克隆

标记

  • 82
  • 19
  • 17
  • 11
  • 8
  • 7
  • 5
  • 4
  • 4
  • 4
  • 4
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  • 3
  • 3
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This HAVCR1 antibody is conjugated to FITC

应用范围

  • 108
  • 55
  • 49
  • 46
  • 20
  • 15
  • 15
  • 11
  • 11
  • 5
  • 5
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Flow Cytometry (FACS)
  • 抗原表位

    • 36
    • 12
    • 8
    • 8
    • 6
    • 6
    • 5
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 58-289

    原理

    Anti-TIM 1/HAVCR1 Antibody FITC Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E. coli-derived human TIM 1 recombinant protein (Position: Q58-K289).

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    HAVCR1 (Hepatitis A Virus Cellular Receptor 1 (HAVCR1))

    别名

    HAVCR1

    背景

    Background: KIM1 (KIDNEY INJURY MOLECULE 1), also known as HAVCR1, HAVCR or TIM1, is a protein that in humans is encoded by the KIM1 gene. The KIM1 gene is mapped to 5q33.3. Biochemical, mutational, and cell adhesion analyses confirm that Tim1 is capable of homophilic Tim-Tim interactions. The features identified in murine KIM1 are conserved in human KIM1. The KIM1 protein is indeed a receptor for the virus through the infection of canine osteogenic sarcoma cells expressing HAVCR1 with HAV. Using a monoclonal antibody to mouse Tim1, Tim1 is expressed after activation of naive T cells and on T cells differentiated in Th2-polarizing conditions. Ectopic expression of KIM1 during mouse T-cell differentiation leads to production of the Th2-type cytokine Il4, but not the Th1-type cytokine Ifng. KIM1-expressing epithelial cells internalized apoptotic bodies, and Kim1 is ly responsible for phagocytosis in cultured primary rat tubule epithelial cells and in porcine and canine epithelial cell lines.

    Gene Full Name: hepatitis A virus cellular receptor 1

    基因ID

    26762

    UniProt

    Q96D42
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