HSPG2 抗体 (AA 524-701) (Fluoro550)
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Quick Overview for HSPG2 抗体 (AA 524-701) (Fluoro550) (ABIN7997004)
抗原
See all HSPG2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 524-701
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原理
- Anti-Heparan Sulfate Proteoglycan 2/HSPG2 Antibody Fluoro550 Conjugated
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特异性
- No cross reactivity with other proteins.
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交叉反应 (详细)
- No cross-reactivity with other proteins
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预测反应
- Human HSPG2 shares 86% amino acid (aa) sequence identity with mouse HSPG2.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human HSPG2 recombinant protein (Position: F524-K701). Human HSPG2 shares 86% amino acid (aa) sequence identity with mouse HSPG2.
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亚型
- IgG
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应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- HSPG2 (Heparan Sulfate Proteoglycan 2 (HSPG2))
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别名
- HSPG2
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背景
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Background: Perlecan (PLC) also known as HSPG2, is a protein that in humans is encoded by the HSPG2 gene. It is mapped to 1p36.12. Perlecan is highly conserved across species and the available data indicate that it has evolved from ancient ancestors by gene duplication and exonshuffling. Perlecan is a key component of the vascular extracellular matrix, here it interacts with a variety of other matrix components and helps to maintain the endothelial barrier function. It is a potent inhibitor of smooth muscle cell proliferation and is thus thought to help maintain vascular homeostasis. Perlecan can also promote growth factor (e.g., FGF2) activity and thus stimulate endothelial growth and re-generation.
Gene Full Name: heparan sulfate proteoglycan 2
Sequence Similarities: Contains 4 EGF-like domains.
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基因ID
- 3339
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UniProt
- P98160
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途径
- Glycosaminoglycan Metabolic Process, Lipid Metabolism
抗原
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