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HSPG2 抗体 (AA 524-701) (Cy3)

The 兔 多克隆 anti-HSPG2 antibody is suitable to detect HSPG2 in samples from 人. It has been validated for FACS.
产品编号 ABIN7997002
发货至: 中国
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Quick Overview for HSPG2 抗体 (AA 524-701) (Cy3) (ABIN7997002)

抗原

See all HSPG2 抗体
HSPG2 (Heparan Sulfate Proteoglycan 2 (HSPG2))

适用

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宿主

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克隆类型

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多克隆

标记

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This HSPG2 antibody is conjugated to Cy3

应用范围

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Flow Cytometry (FACS)
  • 抗原表位

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    AA 524-701

    原理

    Anti-Heparan Sulfate Proteoglycan 2/HSPG2 Antibody Cy3 Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    预测反应

    Human HSPG2 shares 86% amino acid (aa) sequence identity with mouse HSPG2.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human HSPG2 recombinant protein (Position: F524-K701). Human HSPG2 shares 86% amino acid (aa) sequence identity with mouse HSPG2.

    亚型

    IgG
  • 应用备注

    Flow Cytometry, 1-3 μg/1x106 cells

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    HSPG2 (Heparan Sulfate Proteoglycan 2 (HSPG2))

    别名

    HSPG2

    背景

    Background: Perlecan (PLC) also known as HSPG2, is a protein that in humans is encoded by the HSPG2 gene. It is mapped to 1p36.12. Perlecan is highly conserved across species and the available data indicate that it has evolved from ancient ancestors by gene duplication and exonshuffling. Perlecan is a key component of the vascular extracellular matrix, here it interacts with a variety of other matrix components and helps to maintain the endothelial barrier function. It is a potent inhibitor of smooth muscle cell proliferation and is thus thought to help maintain vascular homeostasis. Perlecan can also promote growth factor (e.g., FGF2) activity and thus stimulate endothelial growth and re-generation.

    Gene Full Name: heparan sulfate proteoglycan 2

    Sequence Similarities: Contains 4 EGF-like domains.

    基因ID

    3339

    UniProt

    P98160

    途径

    Glycosaminoglycan Metabolic Process, Lipid Metabolism
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