HCK 抗体 (AA 14-501) (HRP)
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北京 101111
Quick Overview for HCK 抗体 (AA 14-501) (HRP) (ABIN7996963)
抗原
See all HCK 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 14-501
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原理
- Anti-HCK Antibody HRP Conjugated
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交叉反应 (详细)
- No cross-reactivity with other proteins
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预测反应
- Human HCK shares 89.2%,88.7% amino acid (aa) sequence identity with mouse,rat HCK,respectively.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human HCK recombinant protein (Position: R14-R501). Human HCK shares 89.2% and 88.7% amino acid (aa) sequence identity with mouse and rat HCK, respectively.
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亚型
- IgG
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应用备注
- Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.
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有效期
- 12 months
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- HCK (Hemopoietic Cell Kinase (HCK))
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别名
- HCK
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背景
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Background: The protein encoded by this gene is a member of the Src family of tyrosine kinases. This protein is primarily hemopoietic, particularly in cells of the myeloid and B-lymphoid lineages. It may help couple the Fc receptor to the activation of the respiratory burst. In addition, it may play a role in neutrophil migration and in the degranulation of neutrophils. Multiple isoforms with different subcellular distributions are produced due to both alternative splicing and the use of alternative translation initiation codons, including a non-AUG (CUG) codon.
Gene Full Name: HCK proto-oncogene, Src family tyrosine kinase
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基因ID
- 3055
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UniProt
- P08631
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途径
- Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling
抗原
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