HFE 抗体 (AA 112-227) (Cy3)
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北京 101111
Quick Overview for HFE 抗体 (AA 112-227) (Cy3) (ABIN7996870)
抗原
See all HFE 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 112-227
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原理
- Anti-Hfe Antibody Cy3 Conjugated
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived mouse Hfe recombinant protein (Position: N112-H227).
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亚型
- IgG
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应用备注
- Flow Cytometry, 1-3 μg/1x106 cells
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- HFE (Hemochromatosis (HFE))
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别名
- Hfe
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背景
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Background: Human homeostatic iron regulator protein, also known as the HFE protein (High FE2+), is a protein which in humans is encoded by the HFE gene. Enables transferrin receptor binding activity. Involved in positive regulation of gene expression. Acts upstream of or within hormone biosynthetic process and multicellular organismal iron ion homeostasis. Part of HFE-transferrin receptor complex. Is expressed in brain, choroid invagination, diencephalon roof plate, medulla oblongata part of 4th ventricle choroid plexus, and metencephalon part of 4th ventricle choroid plexus. Used to study hemochromatosis type 1. Human ortholog(s) of this gene implicated in several diseases, including acute porphyria (multiple), arthritis (multiple), bone marrow cancer (multiple), hemochromatosis (multiple), and liver disease (multiple). Orthologous to human HFE (homeostatic iron regulator).
Gene Full Name: homeostatic iron regulator
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基因ID
- 15216
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UniProt
- P70387
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途径
- Transition Metal Ion Homeostasis, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
抗原
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