HFE 抗体 (AA 82-199) (Fluoro647)
Our Local Distributor
北京 101111
Quick Overview for HFE 抗体 (AA 82-199) (Fluoro647) (ABIN7996867)
抗原
See all HFE 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 82-199
-
原理
- Anti-HFE Antibody Fluoro647 Conjugated
-
特异性
- No cross reactivity with other proteins.
-
交叉反应 (详细)
- No cross-reactivity with other proteins.
-
预测反应
- Human HFE shares 72.2%,74.6% amino acid (aa) sequence identity with mouse,rat HFE,respectively.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- E.coli-derived human HFE recombinant protein (Position: Q82-R199). Human HFE shares 72.2% and 74.6% amino acid (aa) sequence identity with mouse and rat HFE, respectively.
-
亚型
- IgG
-
-
-
-
应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
-
有效期
- 12 months
-
-
- HFE (Hemochromatosis (HFE))
-
别名
- HFE
-
背景
-
Background: Human hemochromatosis protein also known as the HFE protein is a protein which in humans is encoded by the HFE gene. The HFE gene is located on short arm of chromosome 6 at location 6p21.3. The protein encoded by this gene is a membrane protein that is similar to MHC class I-type proteins and associates with beta2-microglobulin (beta2M). It is thought that this protein functions to regulate iron absorption by regulating the interaction of the transferrin receptor with transferrin. The iron storage disorder, hereditary haemochromatosis, is a recessive genetic disorder that results from defects in this gene.
Gene Full Name: homeostatic iron regulator
-
基因ID
- 3077
-
UniProt
- Q30201
-
途径
- Transition Metal Ion Homeostasis, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
抗原
-