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HSPA9 抗体 (C-Term) (APC)

The APC-conjugated 兔 多克隆 anti-HSPA9 antibody (ABIN7996502) specifically detects HSPA9 in FACS. The antibody is reactive with 人, 大鼠 和 小鼠 samples.
产品编号 ABIN7996502
发货至: 中国
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Quick Overview for HSPA9 抗体 (C-Term) (APC) (ABIN7996502)

抗原

See all HSPA9 抗体
HSPA9 (Heat Shock 70kDa Protein 9 (Mortalin) (HSPA9))

适用

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人, 大鼠, 小鼠

宿主

  • 100
  • 32

克隆类型

  • 97
  • 35
多克隆

标记

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This HSPA9 antibody is conjugated to APC

应用范围

  • 83
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Flow Cytometry (FACS)
  • 抗原表位

    • 45
    • 15
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    C-Term

    原理

    Anti-Grp75/HSPA9 Antibody APC Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    预测反应

    identical to the related mouse,rat sequences.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the C-terminus of human Grp75, identical to the related mouse and rat sequences.

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    HSPA9 (Heat Shock 70kDa Protein 9 (Mortalin) (HSPA9))

    别名

    HSPA9

    背景

    Background: HSPA9 (heat shock 70 kDa protein 9 (mortalin)), also known as GRP75, mot-2, mthsp75, PBP74, HSPA9B, MORTALIN or MORTALIN, PERINUCLEAR, is a highly conserved member of the HSP70 family of proteins. It functions as a chaperone in the mitochondria, cytoplasm, and centrosome. The HSPA9 gene is mapped to chromosome 5q31.2 based on an alignment of the HSPA9 sequence with the genomic sequence. Knockdown of HSPA9 in erythroid cultures was associated with an increased number of cells in the G0/G1 phase of the cell cycle and accelerated apoptosis. Knockdown of Hspa9 in mouse bone marrow cells, followed by transplantation into wildtype recipients, also resulted in loss of erythroid cell number. Haploinsufficiency for HSPA9 may contribute to abnormal hematopoiesis in myelodysplastic syndromes. This protein plays a role in the control of cell proliferation.

    Gene Full Name: heat shock protein family A (Hsp70) member 9

    Sequence Similarities: Contains 1 HMG box DNA-binding domain.

    基因ID

    3313

    UniProt

    P38646
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